Background Transcranial direct current stimulation has shown promising clinical results,
leading to increased demand for an evidence-based review on its clinical effects. Objective …

The salience network (SN) plays a central role in cognitive control by integrating sensory
input to guide attention, attend to motivationally salient stimuli and recruit appropriate …

Depression is a syndrome of stress-and emotion-dysregulation, involving compromised
structural integrity of frontal-limbic networks. Meta-analytic evidence indicates that volumetric …

Depression, a severe psychiatric disorder, has been studied for decades, but the underlying
mechanisms still remain largely unknown. Depression is closely associated with alterations …

Objective Social cognitive deficits can contribute to risk for depression and to psychosocial
impairment during depression. However, available evidence suggests that emotion …

We present a comprehensive overview of the neurobiology of unipolar major depression
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …

BackgroundThere is evidence to suggest that cognitive deficits might persist beyond the
acute stages of illness in major depressive disorder (MDD). However, the findings are …

Corticostriatal circuits through the orbitofrontal cortex (OFC) play key roles in complex
human behaviors such as evaluation, affect regulation and reward-based decision-making …

Background Longitudinal studies of illness progression in patients with major depressive
disorder (MDD) indicate that the onset of subsequent depressive episodes becomes …

The high comorbidity of Major Depressive Disorder (MDD), Anxiety Disorders (ANX), and
Posttraumatic Stress Disorder (PTSD) has hindered the study of their structural neural …