Chemical tools for studying TLR signaling dynamics

T Oosenbrug, MJ van de Graaff, ME Ressing… - Cell chemical …, 2017 - cell.com
The detection of infectious pathogens is essential for the induction of antimicrobial immune
responses. The innate immune system detects a wide array of microbes using a limited set …

Two-photon excitable photoremovable protecting groups based on the quinoline scaffold for use in biology

ALK Hennig, D Deodato, N Asad… - The Journal of …, 2019 - ACS Publications
Photoremovable protecting groups (PPGs) are powerful tools for physiological studies,
harnessing light as an on/off switch to provide tight spatio-temporal control over the release …

Spatial and temporal control of T cell activation using a photoactivatable agonist

E Sanchez, M Huse - Journal of Visualized Experiments: JoVE, 2018 - pmc.ncbi.nlm.nih.gov
T lymphocytes engage in rapid, polarized signaling, occurring within minutes following TCR
activation. This induces formation of the immunological synapse, a stereotyped cell-cell …

[PDF][PDF] Sha** innate immune responses: mechanisms that control t pe I interferon production

T Oosenbrug - Chem. Biol, 2006 - scholarlypublications …
Sha** innate immune responses: mechanisms that control t pe I interferon production
Sha** innate immune responses: mechanisms that control t pe I interferon production …