Double-membrane vesicles as platforms for viral replication
G Wolff, CE Melia, EJ Snijder, M Bárcena - Trends in microbiology, 2020 - cell.com
Viruses, as obligate intracellular parasites, exploit cellular pathways and resources in a
variety of fascinating ways. A striking example of this is the remodelling of intracellular …
variety of fascinating ways. A striking example of this is the remodelling of intracellular …
Lipid droplet contact sites in health and disease
After having been disregarded for a long time as inert fat drops, lipid droplets (LDs) are now
recognized as ubiquitous cellular organelles with key functions in lipid biology and beyond …
recognized as ubiquitous cellular organelles with key functions in lipid biology and beyond …
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators
Viruses are obligate intracellular parasites that make use of the host metabolic machineries
to meet their biosynthetic needs. Thus, identifying the host pathways essential for the virus …
to meet their biosynthetic needs. Thus, identifying the host pathways essential for the virus …
Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formation
Positive-strand RNA viruses replicate in close association with rearranged intracellular
membranes. For hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus …
membranes. For hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus …
The double-membrane vesicle (DMV): a virus-induced organelle dedicated to the replication of SARS-CoV-2 and other positive-sense single-stranded RNA viruses
Positive single-strand RNA (+ RNA) viruses can remodel host cell membranes to induce a
replication organelle (RO) isolating the replication of their genome from innate immunity …
replication organelle (RO) isolating the replication of their genome from innate immunity …
Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection
Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …
infection has become a global pandemic due to the high viral transmissibility and …
Interplay between lipid metabolism, lipid droplets, and DNA virus infections
MA Farías, B Diethelm-Varela, AJ Navarro, AM Kalergis… - Cells, 2022 - mdpi.com
Lipid droplets (LDs) are cellular organelles rich in neutral lipids such as triglycerides and
cholesterol esters that are coated by a phospholipid monolayer and associated proteins …
cholesterol esters that are coated by a phospholipid monolayer and associated proteins …
Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation
Double membrane vesicles (DMVs) serve as replication organelles of plus-strand RNA
viruses such as hepatitis C virus (HCV) and SARS-CoV-2. Viral DMVs are morphologically …
viruses such as hepatitis C virus (HCV) and SARS-CoV-2. Viral DMVs are morphologically …
DEAD/H-box helicases: Anti-viral and pro-viral roles during infections
R Ullah, J Li, P Fang, S **ao, L Fang - Virus Research, 2022 - Elsevier
Abstract DEAD/H-box RNA helicases make the prominent family of helicases super family-2
which take part in almost all RNA-related processes, from initiation of transcription to RNA …
which take part in almost all RNA-related processes, from initiation of transcription to RNA …
Hijacking of lipid droplets by hepatitis C, dengue and zika viruses—from viral protein moonlighting to extracellular release
APM Cloherty, AD Olmstead, CMS Ribeiro… - International journal of …, 2020 - mdpi.com
Hijacking and manipulation of host cell biosynthetic pathways by human enveloped viruses
are essential for the viral lifecycle. Flaviviridae members, including hepatitis C, dengue and …
are essential for the viral lifecycle. Flaviviridae members, including hepatitis C, dengue and …