COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022‏ - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021‏ - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study

OT Ranzani, MDT Hitchings, M Dorion, TL D'Agostini… - bmj, 2021‏ - bmj.com
Objective To estimate the effectiveness of the inactivated whole virus vaccine, CoronaVac
(Sinovac Biotech), against symptomatic covid-19 in the elderly population of São Paulo …

Nanotechnology-based strategies against SARS-CoV-2 variants

X Huang, E Kon, X Han, X Zhang, N Kong… - Nature …, 2022‏ - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already infected more
than 500 million people globally (as of May 2022), creating the coronavirus disease 2019 …

Waves and variants of SARS-CoV-2: understanding the causes and effect of the COVID-19 catastrophe

V Thakur, S Bhola, P Thakur, SKS Patel, S Kulshrestha… - Infection, 2022‏ - Springer
The coronavirus disease-19 has left a permanent mark on the history of the human race.
Severe acute respiratory syndrome coronavirus-2 is a positive-sense single-stranded RNA …

Pan-sarbecovirus neutralizing antibodies in BNT162b2-immunized SARS-CoV-1 survivors

CW Tan, WN Chia, BE Young, F Zhu… - … England Journal of …, 2021‏ - Mass Medical Soc
Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of
concern pose a challenge to the effectiveness of current vaccines. A vaccine that could …

SARS‐CoV‐2 variants and vulnerability at the global level

VP Chavda, AB Patel… - Journal of medical …, 2022‏ - Wiley Online Library
Numerous variants of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
pandemic have evolved. Viral variants may evolve with harmful susceptibility to the immunity …

SARS-CoV-2 mutations and their impact on diagnostics, therapeutics and vaccines

S Thakur, S Sasi, SG Pillai, A Nag, D Shukla… - Frontiers in …, 2022‏ - frontiersin.org
With the high rate of COVID-19 infections worldwide, the emergence of SARS-CoV-2
variants was inevitable. Several mutations have been identified in the SARS-CoV-2 …

The impact of evolving SARS-CoV-2 mutations and variants on COVID-19 vaccines

G McLean, J Kamil, B Lee, P Moore, TF Schulz, A Muik… - MBio, 2022‏ - journals.asm.org
The emergence of several new variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in recent months has raised concerns around the potential impact on …

Reinfection in patients with COVID-19: a systematic review

X Ren, J Zhou, J Guo, C Hao, M Zheng… - Global health research …, 2022‏ - Springer
Background With the continuation of the COVID-19 pandemic, some COVID-19 patients
have become reinfected with the virus. Viral gene sequencing has found that some of these …