Modern-day environmental factors in the pathogenesis of osteoarthritis
The prevalence of osteoarthritis (OA) is rising for reasons that are not fully understood. In this
Opinion article, we review the possibility that OA is an evolutionary mismatch disease, which …
Opinion article, we review the possibility that OA is an evolutionary mismatch disease, which …
[HTML][HTML] Fundamentals of OA. An initiative of Osteoarthritis and Cartilage. Obesity and metabolic factors in OA
Objective Obesity was once considered a risk factor for knee osteoarthritis (OA) primarily for
biomechanical reasons. Here we provide an additional perspective by discussing how …
biomechanical reasons. Here we provide an additional perspective by discussing how …
Bioinformatics-led discovery of osteoarthritis biomarkers and inflammatory infiltrates
X Hu, S Ni, K Zhao, J Qian, Y Duan - Frontiers in immunology, 2022 - frontiersin.org
The molecular mechanisms of osteoarthritis, the most common chronic disease, remain
unexplained. This study aimed to use bioinformatic methods to identify the key biomarkers …
unexplained. This study aimed to use bioinformatic methods to identify the key biomarkers …
Metabolic syndrome-associated osteoarthritis
Metabolic syndrome-associated osteoarthritis : Current Opinion in Rheumatology Metabolic
syndrome-associated osteoarthritis : Current Opinion in Rheumatology Log in or Register …
syndrome-associated osteoarthritis : Current Opinion in Rheumatology Log in or Register …
Metabolic regulation of inflammation in osteoarthritis
Osteoarthritis (OA) has long been considered the unique consequence of a wear and tear
process leading to cartilage degradation. Indeed, it is true that excessive mechanical stress …
process leading to cartilage degradation. Indeed, it is true that excessive mechanical stress …
[HTML][HTML] Relationship between inflammation, the gut microbiota, and metabolic osteoarthritis development: studies in a rat model
Osteoarthritis (OA) may result from intrinsic inflammation related to metabolic disturbance.
Obesity-associated inflammation is triggered by lipopolysaccharide (LPS) derived from the …
Obesity-associated inflammation is triggered by lipopolysaccharide (LPS) derived from the …
Polyunsaturated fatty acids and inflammation
Inflammation is a protective process for life that aims to restore body homeostasis by
targeting the injury and by inducing repair mechanisms. This process can also become …
targeting the injury and by inducing repair mechanisms. This process can also become …
[HTML][HTML] Osteoarthritis year in review 2015: biology
AM Malfait - Osteoarthritis and Cartilage, 2016 - Elsevier
This review highlights a selection of recently published literature in the area of osteoarthritis
biology. Major themes transpiring from a PubMed search covering the year between the …
biology. Major themes transpiring from a PubMed search covering the year between the …
Fatty acids and oxylipins in osteoarthritis and rheumatoid arthritis—A complex field with significant potential for future treatments
AM Mustonen, P Nieminen - Current rheumatology reports, 2021 - Springer
Abstract Purpose of Review Osteoarthritis (OA) and rheumatoid arthritis (RA) are
characterized by abnormal lipid metabolism manifested as altered fatty acid (FA) profiles of …
characterized by abnormal lipid metabolism manifested as altered fatty acid (FA) profiles of …
Sex specific determinants in osteoarthritis: a systematic review of preclinical studies
D Contartese, M Tschon, M De Mattei… - International journal of …, 2020 - mdpi.com
Osteoarthritis (OA) is a highly prevalent joint disease that primarily affects about 10% of the
world's population over 60 years old. The purpose of this study is to systematically review …
world's population over 60 years old. The purpose of this study is to systematically review …