According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

Shotgun proteomics aims to identify and quantify the thousands of proteins in complex
mixtures such as cell and tissue lysates and biological fluids. This approach uses liquid …

Mass spectrometry is unmatched in its versatility for studying practically any aspect of the
proteome. Because the foundations of mass spectrometry-based proteomics are complex …

Summary mRNAs continually change their protein partners throughout their lifetimes, yet our
understanding of mRNA-protein complex (mRNP) remodeling is limited by a lack of temporal …

Comprehensive, reproducible and precise analysis of large sample cohorts is one of the key
objectives of quantitative proteomics. Here, we present an implementation of data …

We characterized a prospective endometrial carcinoma (EC) cohort containing 138 tumors
and 20 enriched normal tissues using 10 different omics platforms. Targeted quantitation of …

We report proteogenomic analysis of diffuse gastric cancers (GCs) in young populations.
Phosphoproteome data elucidated signaling pathways associated with somatic mutations …

Adenosine triphosphate (ATP) plays fundamental roles in cellular biochemistry and was
recently discovered to function as a biological hydrotrope. Here, we use mass spectrometry …

Mass spectrometry (MS)-based ubiquitinomics provides system-level understanding of
ubiquitin signaling. Here we present a scalable workflow for deep and precise in vivo …

Efforts to precisely identify tumor human leukocyte antigen (HLA) bound peptides capable of
mediating T cell-based tumor rejection still face important challenges. Recent studies …