Tumor-associated macrophages (TAMs) are major innate immune cells that constitute up to
50% of the cell mass of human tumors. TAMs are highly heterogeneous cells that originate …

Breast cancer is presently the most predominant tumor type and the second leading cause
of tumor-related deaths among women. Although advancements in diagnosis and …

Tumor-associated macrophages (TAMs) are important tumor-promoting cells in the breast
tumor microenvironment. Preclinically TAMs stimulate breast tumor progression, including …

Inflammation is a recognised hallmark of cancer that substantially contributes to the
development and progression of malignancies. In established cancers, there is increasing …

Simple Summary Chronic inflammation is an important cause of multiple cancers. While
chronic inflammation is present in breast cancer and may influence its outcome, its role in …

Background The prognostic values of tumor-infiltrating lymphocytes (TILs) and TILs subsets
in breast cancer (BC) are uncertain. Methods A systematic literature search (MEDLINE, Web …

Tertiary lymphoid structures (TLS) are ectopic cellular aggregates that resemble secondary
lymphoid organs in their composition and structural organization. In contrast to secondary …

Summary PD-L1 and PD-L2 constitute an important antitumor immune response. In breast
cancer, their prognostic value is still to be defined. In this study, we investigate the …

Abstract Introduction Tumor-associated macrophages (TAMs) in breast cancer are
associated with a poor prognosis. Early studies of TAMs were largely limited to the pan …

Background: The elevation of the platelet-to-lymphocyte ratio (PLR), an easily applicable
blood test based on platelet and lymphocyte counts has been associated with poor …