N 6-Methyladenosine (m 6 A) RNA modification brings a new dawn for RNA modification
researches in recent years. This posttranscriptional RNA modification is dynamic and …

Summary DNA N 6-methyldeoxyadenosine (6mA) modification was first discovered in
Bacterium coli in the 1950s. Over the next several decades, 6mA was recognized as a …

Although various methods have been developed for sequencing cytosine modifications, it is
still challenging for specific and quantitative sequencing of individual modification at base …

DNA storage has shown potential to transcend current silicon-based data storage
technologies in storage density, longevity and energy consumption,–. However, writing large …

Exploring spatial organization and relationship of diverse biomolecules within cellular
nanoenvironments is important to elucidate the fundamental processes of life. However, it …

Background In mammals, modifications to cytosine bases, particularly in cytosine-guanine
(CpG) dinucleotide contexts, play a major role in sha** the epigenome. The canonical …

The detection of DNA methylation with high sensitivity and specificity is important for the
early diagnosis of many human diseases, including cancers. Here, we integrated the high …

In this work, a novel electrochemical biosensor is developed for facile and highly sensitive
detection of lipopolysaccharide (LPS) based on collaboration of dual enzymes for multiple …

Assessing the activity of DNA methyltransferases (MTases) and screening for
methyltransferase inhibitors not only allow for a deep exploration of the role of methylation …

Osteoporosis is an age-related, systemic skeletal disease that poses a significant public
health challenge in contemporary society. Development at the epigenetic level is emerging …