The presence of an abnormal amount of single-stranded DNA in the bacterial cell constitutes
a genotoxic alarm signal that induces the SOS response, a broad regulatory network found …

When describing the structure of the DNA double helix, Watson and Crick (1) wrote,“It has
not escaped our notice that the specific pairing we have postulated immediately suggests a …

SUMMARY DNA repair and DNA damage tolerance machineries are crucial to overcome
the vast array of DNA damage that a cell encounters during its lifetime. In this review, we …

The emergence of drug-resistant bacteria poses a serious threat to human health. In the
case of several antibiotics, including those of the quinolone and rifamycin classes, bacteria …

Nucleotide excision repair (NER) is a major cellular defense against the carcinogenic effects
of ultraviolet light from the sun. Mutational inactivation of NER proteins, like DDB and CSA …

Monoubiquitination is a reversible post-translational protein modification that has an
important regulatory function in many biological processes, including DNA repair …

Numerous agents of endogenous and exogenous origin damage DNA in our genome.
There are several DNA‐repair pathways that recognize lesions in DNA and remove them …

Photodynamic inactivation of microorganisms (aPDI) is an excellent method to destroy
antibiotic-resistant microbial isolates. The use of an exogenous photosensitizer or irradiation …

The American Association for Cancer Research has been the citadel for communicating
research on chemical carcinogens for over a century. It therefore seems appropriate that a …

Alcoholic beverage consumption is classified as a known human carcinogen, causally
related to an increased risk of cancer of the upper gastrointestinal tract. The formation of …