Coronary artery disease (CAD) is the most common health problem worldwide and remains
the leading cause of morbidity and mortality. Over the past decade, it has become clear that …

Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

The pursuit to discover the fundamental biology and mechanisms of aging within the context
of the physical and social environment is critical to designing interventions to prevent and …

Although dysregulated cholesterol metabolism predisposes aging tissues to inflammation
and a plethora of diseases, the underlying molecular mechanism remains poorly defined …

Lipid metabolism plays crucial roles in cellular processes such as hormone synthesis,
energy production, and fat storage. Older adults are at risk of the dysregulation of lipid …

The aim of the present review paper is to survey the literature related to DNA methylation,
and its association with cancer and ageing. The review will outline the key factors, including …

Cholesterol metabolism plays an essential role in cellular functions (including as a
component of the plasma membrane, as an energy source, and in hormone production) …

Vitamin D and cholesterol metabolism overlap significantly in the pathways that contribute to
their biosynthesis. However, our understanding of their independent and co-regulation is …

Metabolic disorders, such as obesity, elevated blood pressure, dyslipidemias, insulin
resistance, hyperglycemia, and hyperuricemia have all been identified as risk factors for an …

Sirtuin 1 (SIRT1) enzyme plays a pivotal role in the regulation of many physiological
functions. In particular, it is implicated in ageing‐related diseases, such as cardiac …