Organisms of all domains of life use photoreceptor proteins to sense and respond to light.
The light-sensitivity of photoreceptor proteins arises from bound chromophores such as …

Cell–material interactions constitute a key fundamental topic in biomaterials study. Various
cell cues and matrix cues as well as soluble factors regulate cell behaviors on materials …

Bacteriorhodopsin (bR) is a light-driven proton pump and a model membrane transport
protein. We used time-resolved serial femtosecond crystallography at an x-ray free electron …

G-protein-coupled receptors comprise the largest family of mammalian transmembrane
receptors. They mediate numerous cellular pathways by coupling with downstream …

The first structure of a flavivirus has been determined by using a combination of cryoelectron
microscopy and fitting of the known structure of glycoprotein E into the electron density map …

Organic molecules as well as metal complexes may exist as several geometric isomers1
which display distinct physical properties and chemical reactivities. A molecule containing …

Molecular machines, such as polymerases, ribosomes, or proteasomes, fulfill complex tasks
requiring the thermal energy of their environment. They achieve this by restricting random …

Single-particle cryogenic electron microscopy (cryo-EM) allows reconstruction of high-
resolution structures of proteins in different conformations. Protein function often involves …

Cryo‐electron microscopy (cryo‐EM) is increasingly becoming a mainstream technology for
studying the architecture of cells, viruses and protein assemblies at molecular resolution …

G protein coupled receptors (GPCRs) are remarkably versatile signaling molecules. The
members of this large family of membrane proteins are activated by a spectrum of …