[HTML][HTML] Exosome theranostics: biology and translational medicine

C He, S Zheng, Y Luo, B Wang - Theranostics, 2018 - ncbi.nlm.nih.gov
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules,
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …

Exosomes: the next generation of endogenous nanomaterials for advanced drug delivery and therapy

W Liao, Y Du, C Zhang, F Pan, Y Yao, T Zhang, Q Peng - Acta biomaterialia, 2019 - Elsevier
Abstract Development of functional nanomaterials is of great importance and significance for
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …

Exosome-shuttled miR-216a-5p from hypoxic preconditioned mesenchymal stem cells repair traumatic spinal cord injury by shifting microglial M1/M2 polarization

W Liu, Y Rong, J Wang, Z Zhou, X Ge, C Ji… - Journal of …, 2020 - Springer
Background Spinal cord injury (SCI) can lead to severe motor and sensory dysfunction with
high disability and mortality. In recent years, mesenchymal stem cell (MSC)-secreted nano …

Microneedle patch loaded with exosomes containing microRNA‐29b prevents cardiac fibrosis after myocardial infarction

J Yuan, H Yang, C Liu, L Shao, H Zhang… - Advanced …, 2023 - Wiley Online Library
Myocardial infarction (MI) is a cardiovascular disease that poses a serious threat to human
health. Uncontrolled and excessive cardiac fibrosis after MI has been recognized as a …

Electrochemical biosensor for ultrasensitive exosomal miRNA analysis by cascade primer exchange reaction and MOF@ Pt@ MOF nanozyme

X Li, X Li, D Li, M Zhao, H Wu, B Shen, P Liu… - Biosensors and …, 2020 - Elsevier
Exosomal miRNAs have been discovered as important and reliable biomarkers for early
diagnosis of tumors. However, it is still challenging to achieve accurate determination of …

Exosomes: new molecular targets of diseases

S Samanta, S Rajasingh, N Drosos, Z Zhou… - Acta Pharmacologica …, 2018 - nature.com
Extracellular vesicles (EVs) comprise apoptotic bodies, microvesicles and exosomes, and
they perform as key regulators in cell-to-cell communication in normal as well as diseased …

Engineered exosomes with ischemic myocardium‐targeting peptide for targeted therapy in myocardial infarction

X Wang, Y Chen, Z Zhao, Q Meng, Y Yu… - Journal of the …, 2018 - Am Heart Assoc
Background Exosomes are membranous vesicles generated by almost all cells. Recent
studies demonstrated that mesenchymal stem cell–derived exosomes possessed many …

A comparative study of serum exosome isolation using differential ultracentrifugation and three commercial reagents

I Helwa, J Cai, MD Drewry, A Zimmerman, MB Dinkins… - PloS one, 2017 - journals.plos.org
Exosomes play a role in cell-to-cell signaling and serve as possible biomarkers. Isolating
exosomes with reliable quality and substantial concentration is a major challenge. Our …

Inside (sight) of tiny communicator: exosome biogenesis, secretion, and uptake

AS Jadli, N Ballasy, P Edalat, VB Patel - Molecular and cellular …, 2020 - Springer
Discovered in the late 1980s as an extracellular vesicle of endosomal origin secreted from
reticulocytes, exosomes recently gained scientific attention due to its role in intercellular …

[HTML][HTML] Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction

K Essandoh, L Yang, X Wang, W Huang, D Qin… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Sepsis is an infection-induced severe inflammatory disorder that leads to multiple organ
failure. Amongst organs affected, myocardial depression is believed to be a major …