Clinical intervention using focused ultrasound (FUS) stimulation of the brain in diverse neurological disorders

H Baek, D Lockwood, EJ Mason, E Obusez… - Frontiers in …, 2022 - frontiersin.org
Various surgical techniques and pharmaceutical treatments have been developed to
improve the current technologies of treating brain diseases. Focused ultrasound (FUS) is a …

Outcome and complications of MR guided focused ultrasound for essential tremor: a systematic review and meta-analysis

M Agrawal, K Garg, R Samala, R Rajan, V Naik… - Frontiers in …, 2021 - frontiersin.org
Background: Magnetic resonance guided focused ultrasound (MRgFUS) is a relatively novel
technique to treat essential tremor (ET). The objective of this review was to analyze the …

Bilateral focused ultrasound thalamotomy for essential tremor (BEST‐FUS phase 2 trial)

C Iorio‐Morin, K Yamamoto, C Sarica… - Movement …, 2021 - Wiley Online Library
Background In patients with medically refractory essential tremor, unilateral magnetic
resonance–guided focused ultrasound thalamotomy can improve contralateral tremor …

Responsive deep brain stimulation guided by ventral striatal electrophysiology of obsession durably ameliorates compulsion

YH Nho, CE Rolle, U Topalovic, RS Shivacharan… - Neuron, 2024 - cell.com
Treatment-resistant obsessive-compulsive disorder (OCD) occurs in approximately one-third
of OCD patients. Obsessions may fluctuate over time but often occur or worsen in the …

Magnetic resonance imaging–guided focused ultrasound thalamotomy for essential tremor: 5-year follow-up results

GR Cosgrove, N Lipsman, AM Lozano, JW Chang… - Journal of …, 2022 - thejns.org
OBJECTIVE The objective of this study was to evaluate, at 4 and 5 years posttreatment, the
long-term safety and efficacy of unilateral MRI-guided focused ultrasound (MRgFUS) …

Outcomes of focused ultrasound thalamotomy in tremor syndromes

J Peters, J Maamary, K Kyle, N Olsen… - Movement …, 2024 - Wiley Online Library
Background The current literature comparing outcomes after a unilateral magnetic
resonance image–guided focused ultrasound (MRgFUS) thalamotomy between tremor …

Focused ultrasound thalamotomy in tremor dominant Parkinson's disease: long-term results

A Sinai, M Nassar, E Sprecher… - Journal of …, 2022 - content.iospress.com
Background: MRI-guided focused ultrasound (FUS) has established short-term efficacy in
tremor relief. Objective: We report our long-term experience of treating tremor with unilateral …

Lesion location and lesion creation affect outcomes after focused ultrasound thalamotomy

DJ Segar, AM Lak, S Lee, M Harary, V Chavakula… - Brain, 2021 - academic.oup.com
MRI-guided focused ultrasound thalamotomy has been shown to be an effective treatment
for medication refractory essential tremor. Here, we report a clinical-radiological analysis of …

Comparison between deep brain stimulation and magnetic resonance-guided focused ultrasound in the treatment of essential tremor: a systematic review and pooled …

M Giordano, VM Caccavella, I Zaed… - Journal of Neurology …, 2020 - jnnp.bmj.com
The current gold standard surgical treatment for medication-resistant essential tremor (ET) is
deep brain stimulation (DBS). However, recent advances in technologies have led to the …

Focused ultrasound thalamotomy for tremor treatment impacts the cerebello-thalamo-cortical network

L Dahmani, Y Bai, M Li, J Ren, L Shen, J Ma… - npj Parkinson's …, 2023 - nature.com
Abstract High-intensity Magnetic Resonance-guided Focused Ultrasound (MRgFUS) is a
recent, non-invasive line of treatment for medication-resistant tremor. We used MRgFUS to …