Tumor neoantigen is the truly foreign protein and entirely absent from normal human
organs/tissues. It could be specifically recognized by neoantigen-specific T cell receptors …

Adaptive immunity is mediated by T‐and B‐cells, which are immune cells capable of
develo** pathogen‐specific memory that confers immunological protection. Memory and …

Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center …

Breast cancers are complex ecosystems of malignant cells and the tumour
microenvironment. The composition of these tumour ecosystems and interactions within …

Peptide identification in liquid chromatography-tandem mass spectrometry (LC-MS/MS)
experiments relies on computational algorithms for matching acquired MS/MS spectra …

T cell immunity is central for the control of viral infections. To characterize T cell immunity,
but also for the development of vaccines, identification of exact viral T cell epitopes is …

Abstract The Immune Epitope Database (IEDB, iedb. org) captures experimental data
confined in figures, text and tables of the scientific literature, making it freely available and …

Prediction of HLA epitopes is important for the development of cancer immunotherapies and
vaccines. However, current prediction algorithms have limited predictive power, in part …

Cytotoxic T cells are of central importance in the immune system's response to disease.
They recognize defective cells by binding to peptides presented on the cell surface by MHC …

Antibodies have become an indispensable tool for many biotechnological and clinical
applications. They bind their molecular target (antigen) by recognizing a portion of its …