Randomized trial of early detection and treatment of postpartum hemorrhage

I Gallos, A Devall, J Martin, L Middleton… - … England Journal of …, 2023‏ - Mass Medical Soc
Background Delays in the detection or treatment of postpartum hemorrhage can result in
complications or death. A blood-collection drape can help provide objective, accurate, and …

Tranexamic acid versus oxytocin prophylaxis in reducing post-partum blood loss, in low-risk pregnant women: TRANOXY STUDY, a phase III randomized clinical trial

A Ragusa, F Ficarola, A Ferrari, N Spirito… - …, 2024‏ - thelancet.com
Background To assess the equivalence of tranexamic acid (TRAN) versus synthetic oxytocin
(OXY) in reducing post-partum blood loss, in full-term patients (37–42 weeks), at low risk of …

Quality of essential medicines from different sources in Enugu and Anambra, Nigeria

J Gabel, M Lächele, K Sander… - … American Journal of …, 2024‏ - pmc.ncbi.nlm.nih.gov
This study investigated the quality of 13 essential medicines in the states of Enugu and
Anambra, Nigeria. A total of 260 samples were purchased from licensed pharmaceutical …

Post-marketing quality evaluation of oxytocin injection and assessment of associated factors among selected health facilities in Addis Ababa, Ethiopia

AA Alemie, EA Siraj, GB Wondie, DR Soboka… - Scientific Reports, 2024‏ - nature.com
Oxytocin is the principal drug and the primary choice for labor induction and postpartum
hemorrhage prevention and treatment. The problems associated with oxytocin are not …

The compatibility of oxytocin and tranexamic acid injection products when mixed for co‐administration by infusion for the treatment of postpartum haemorrhage: An in …

P Lambert, A Tomazzini, P Wright… - … Journal of Obstetrics …, 2023‏ - Wiley Online Library
Objective To investigate the compatibility of oxytocin and tranexamic acid injection products
when mixed for the purpose of co‐administration by intravenous infusion. Design …

[HTML][HTML] A tale of two medicines: The need for ownership, end-to-end planning and execution for development and introduction of maternal health medicines

M Gülmezoglu, L Chinery, S Rushwan… - … Journal of Maternal …, 2024‏ - pmc.ncbi.nlm.nih.gov
Postpartum hemorrhage (PPH) persists as the leading direct cause of maternal mortality in
low-and middle-income countries (LMICs) and is a major global health challenge. Following …

Understanding the regulatory-procurement interface for medicines in Africa via publicly available information on standards, implementation, and enforcement in five …

JC Kohler, M Castro-Arteaga, S Panjwani… - … Policy and Practice, 2025‏ - Taylor & Francis
Background Substandard and falsified medicines in Africa are a major public health
concern. Access to quality medical products in African countries is governed in large part by …

[HTML][HTML] An implementation research study on uterotonics use patterns and heat-stable carbetocin acceptability and safety for prevention of postpartum hemorrhage in …

OA Amode, OV Negedu, JT Joseph… - … Journal of Maternal …, 2024‏ - pmc.ncbi.nlm.nih.gov
Background and Objective The burden of maternal mortality attributable to postpartum
hemorrhage (PPH) remains high in Nigeria. Currently, oxytocin, and misoprostol, which are …

[PDF][PDF] Improving postpartum hemorrhage care: Policy, practice, and research

C Ameh, F Althabe - 2022‏ - erepository.uonbi.ac.ke
Postpartum hemorrhage (PPH) occurs in around 3%–5% of all births, with large regional
variation. Approximately one-quarter of the annual 300 000 maternal deaths are related to …

Cross-Sectional Survey to Assess Hospital System Readiness for Hemorrhage During and After Cesarean Delivery in Africa

M Crowther, RA Dyer, DG Bishop… - Anesthesia & …, 2022‏ - journals.lww.com
BACKGROUND: Mothers in Africa are 50 times more likely to die after cesarean delivery
(CD) than in high-income countries, largely due to hemorrhage. It is unclear whether …