Insight into cellular uptake and intracellular trafficking of nanoparticles

P Foroozandeh, AA Aziz - Nanoscale research letters, 2018 - Springer
Nanoparticle science is rapidly changing the landscape of various scientific fields and
defining new technological platforms. This is perhaps even more evident in the field of …

Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective

SA Ejazi, R Louisthelmy, K Maisel - ACS nano, 2023 - ACS Publications
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …

Corona composition can affect the mechanisms cells use to internalize nanoparticles

V Francia, K Yang, S Deville, C Reker-Smit, I Nelissen… - ACS …, 2019 - ACS Publications
Nanosized objects, such as nanoparticles and other drug carriers used in nanomedicine,
once in contact with biological environments are modified by adsorption of biomolecules on …

Toxicity in vitro reveals potential impacts of microplastics and nanoplastics on human health: A review

Q Shi, J Tang, R Liu, L Wang - Critical Reviews in Environmental …, 2022 - Taylor & Francis
Microplastics (MPs) have attracted considerable interest on account of their ubiquitous
presence in the environment in recent years. In particular, nanoplastics (NPs), with smaller …

Biomolecular coronas provide the biological identity of nanosized materials

MP Monopoli, C Aberg, A Salvati… - Nano-Enabled Medical …, 2020 - taylorfrancis.com
Fundamentally, all interactions between the nanoparticle corona complex and the biological
machinery are mediated by physical forces common to all molecular systems. The …

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

E Fröhlich - International journal of nanomedicine, 2012 - Taylor & Francis
Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

N Kamaly, Z **ao, PM Valencia… - Chemical Society …, 2012 - pubs.rsc.org
Polymeric materials have been used in a range of pharmaceutical and biotechnology
products for more than 40 years. These materials have evolved from their earlier use as …

Physicochemical characteristics of nanoparticles affect circulation, biodistribution, cellular internalization, and trafficking

X Duan, Y Li - Small, 2013 - Wiley Online Library
Nanoparticles have many potential applications in tumor therapy. Systemically administered
nanoparticles should remain in circulation for a long time to increase their accumulation in …

Nanoparticle adhesion to the cell membrane and its effect on nanoparticle uptake efficiency

A Lesniak, A Salvati, MJ Santos-Martinez… - Journal of the …, 2013 - ACS Publications
The interactions between nanosized particles and living systems are commonly mediated by
what adsorbs to the nanoparticle in the biological environment, its biomolecular corona …

Polystyrene nanoparticles internalization in human gastric adenocarcinoma cells

M Forte, G Iachetta, M Tussellino, R Carotenuto… - Toxicology in Vitro, 2016 - Elsevier
The increase in the use of nanoparticles, as a promising tool for drug delivery or as a food
additive, raises questions about their interaction with biological systems, especially in terms …