Thrombotic complications in 2928 patients with COVID-19 treated in intensive care: a systematic review

WJ Jenner, R Kanji, S Mirsadraee, YX Gue… - Journal of thrombosis …, 2021 - Springer
A prothrombotic state is reported with severe COVID-19 infection, which can manifest in
venous and arterial thrombotic events. Coagulopathy is reflective of more severe disease …

MATH+ protocol for the treatment of SARS-CoV-2 infection: the scientific rationale

PE Marik, P Kory, J Varon, J Iglesias… - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction COVID-19 disease progresses through a number of distinct phases. The
management of each phase is unique and specific. The pulmonary phase of COVID-19 is …

Platelets amplify endotheliopathy in COVID-19

TJ Barrett, MI Cornwell, K Myndzar, CC Rolling… - Science …, 2021 - science.org
Given the evidence for a hyperactive platelet phenotype in COVID-19, we investigated
effector cell properties of COVID-19 platelets on endothelial cells (ECs). Integration of EC …

Relative hypercoagulopathy of the SARS-CoV-2 beta and delta variants when compared to the less severe omicron variants is related to TEG parameters, the extent of …

LM Grobbelaar, A Kruger, C Venter… - … in thrombosis and …, 2022 - thieme-connect.com
Earlier variants of SARS-CoV-2 have been associated with hypercoagulability and an
extensive formation of fibrin amyloid microclots, which are considered to contribute to the …

Prevalence of readily detected amyloid blood clots in 'unclotted'Type 2 diabetes mellitus and COVID-19 plasma: a preliminary report

E Pretorius, C Venter, GJ Laubscher… - Cardiovascular …, 2020 - Springer
Abstract Background Type 2 Diabetes Mellitus (T2DM) is a well-known comorbidity to
COVID-19 and coagulopathies are a common accompaniment to both T2DM and COVID-19 …

Viscoelastometric testing to assess hemostasis of COVID-19: a systematic review

M Bareille, M Hardy, J Douxfils, S Roullet… - Journal of Clinical …, 2021 - mdpi.com
Infection by SARS-CoV-2 is associated with a high risk of thrombosis. The laboratory
documentation of hypercoagulability and impaired fibrinolysis remains a challenge. Our aim …

The role of TEG analysis in patients with COVID-19-associated coagulopathy: a systematic review

J Hartmann, A Ergang, D Mason, JD Dias - Diagnostics, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19)-associated coagulopathy (CAC), characterized by
hypercoagulability and an increased risk of thrombotic complications, is an important …

Platelet reactivity to thrombin differs between patients with COVID-19 and those with ARDS unrelated to COVID-19

Y Zaid, F Guessous, F Puhm, W Elhamdani… - Blood …, 2021 - ashpublications.org
In addition to preserving homeostasis and contributing to immunity, platelets may exhibit a
dysregulated state1, 2 in acute respiratory distress syndrome (ARDS) and potentially …

A review of pathophysiology, clinical features, and management options of COVID-19 associated coagulopathy

J Goswami, TA MacArthur, M Sridharan, RK Pruthi… - Shock, 2021 - journals.lww.com
There is increasing evidence that novel coronavirus disease 2019 (COVID-19) leads to a
significant coagulopathy, a phenomenon termed “COVID-19 associated coagulopathy.” …

Anticoagulation and in-hospital mortality from coronavirus disease 2019: a systematic review and meta-analysis

C Moonla, D Sosothikul, T Chiasakul… - Clinical and Applied …, 2021 - journals.sagepub.com
Hypercoagulability in coronavirus disease 2019 (COVID-19) may aggravate disease
severity during hospitalization but the reported survival benefits from anticoagulation (AC) …