Converging concepts of protein folding in vitro and in vivo

FU Hartl, M Hayer-Hartl - Nature structural & molecular biology, 2009 - nature.com
Most proteins must fold into precise three-dimensional conformations to fulfill their biological
functions. Here we review recent concepts emerging from studies of protein folding in vitro …

Rubisco activity and regulation as targets for crop improvement

MAJ Parry, PJ Andralojc, JC Scales… - Journal of …, 2013 - academic.oup.com
Abstract Rubisco (ribulose-1, 5-bisphosphate (RuBP) carboxylase/oxygenase) enables net
carbon fixation through the carboxylation of RuBP. However, some characteristics of …

Rubisco condensate formation by CcmM in β-carboxysome biogenesis

H Wang, X Yan, H Aigner, A Bracher, ND Nguyen… - Nature, 2019 - nature.com
Cells use compartmentalization of enzymes as a strategy to regulate metabolic pathways
and increase their efficiency. The α-and β-carboxysomes of cyanobacteria contain ribulose …

A faster Rubisco with potential to increase photosynthesis in crops

MT Lin, A Occhialini, PJ Andralojc, MAJ Parry… - Nature, 2014 - nature.com
In photosynthetic organisms, d-ribulose-1, 5-bisphosphate carboxylase/oxygenase
(Rubisco) is the major enzyme assimilating atmospheric CO2 into the biosphere. Owing to …

Plant RuBisCo assembly in E. coli with five chloroplast chaperones including BSD2

H Aigner, RH Wilson, A Bracher, L Calisse, JY Bhat… - Science, 2017 - science.org
Plant RuBisCo, a complex of eight large and eight small subunits, catalyzes the fixation of
CO2 in photosynthesis. The low catalytic efficiency of RuBisCo provides strong motivation to …

Biogenesis and metabolic maintenance of Rubisco

A Bracher, SM Whitney, FU Hartl… - Annual review of plant …, 2017 - annualreviews.org
Ribulose-1, 5-bisphosphate carboxylase/oxygenase (Rubisco) mediates the fixation of
atmospheric CO2 in photosynthesis by catalyzing the carboxylation of the 5-carbon sugar …

Assembly, function and evolution of cyanobacterial carboxysomes

CA Kerfeld, MR Melnicki - Current opinion in plant biology, 2016 - Elsevier
Highlights•Alpha and beta carboxysomes differ in composition, assembly, and
evolution.•Alphas appear to co-assemble shell and cargo proteins; betas assemble inside …

Advancing Our Understanding and Capacity to Engineer Nature's CO2-Sequestering Enzyme, Rubisco

SM Whitney, RL Houtz, H Alonso - Plant physiology, 2011 - academic.oup.com
There is a growing impetus in develo** novel strategies to address global concerns
regarding food security. As crop productivity gains through traditional breeding begin to lag …

Engineering chloroplasts to improve Rubisco catalysis: prospects for translating improvements into food and fiber crops

RE Sharwood - New Phytologist, 2017 - Wiley Online Library
The uncertainty of future climate change is placing pressure on crop** systems to
continue to provide stable increases in productive yields. To mitigate future climates and the …

Surveying Rubisco diversity and temperature response to improve crop photosynthetic efficiency

DJ Orr, A Alcântara, MV Kapralov, PJ Andralojc… - Plant …, 2016 - academic.oup.com
The threat to global food security of stagnating yields and population growth makes
increasing crop productivity a critical goal over the coming decades. One key target for …