Tumor cell infiltration into the brain in glioblastoma: from mechanisms to clinical perspectives

F Seker-Polat, N Pinarbasi Degirmenci, I Solaroglu… - Cancers, 2022 - mdpi.com
Simple Summary The estimated survival time for glioblastoma patients is extremely low; only
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …

Surgical management of Glioma Grade 4: technical update from the neuro-oncology section of the Italian Society of Neurosurgery (SINch®): a systematic review

T Ius, G Sabatino, PP Panciani, MM Fontanella… - Journal of neuro …, 2023 - Springer
Purpose The extent of resection (EOR) is an independent prognostic factor for overall
survival (OS) in adult patients with Glioma Grade 4 (GG4). The aim of the neuro-oncology …

Fluorescence-guided surgery in glioblastoma: 5-ALA, SF or both? Differences between fluorescent dyes in 99 consecutive cases

P Zeppa, R De Marco, M Monticelli, A Massara… - Brain Sciences, 2022 - mdpi.com
Background: Glioblastoma (GBM) is the most common primary brain tumor. The extent of
resection (EOR) has been claimed as one of the most important prognostic factors …

A systematic review of amino acid PET imaging in adult-type high-grade glioma surgery: a neurosurgeon's perspective

R De Marco, A Pesaresi, A Bianconi, M Zotta… - Cancers, 2022 - mdpi.com
Simple Summary Several advantages of molecular imaging, namely, positron emission
tomography (PET), have been already described in different settings of glioma management …

[HTML][HTML] Single mesenchymal stromal cell migration tracking into glioblastoma using photoconvertible vesicles

OA Sindeeva, PA Demina, ZV Kozyreva… - Nanomaterials, 2024 - mdpi.com
Reliable cell labeling and tracking techniques are imperative for elucidating the intricate and
ambiguous interactions between mesenchymal stromal cells (MSCs) and tumors. Here, we …

Resection of the contrast-enhancing tumor in diffuse gliomas bordering eloquent areas using electrophysiology and 5-ALA fluorescence: evaluation of resection rates …

DR Peters, F Halimi, K Ozduman, M Levivier… - Neurosurgical …, 2023 - Springer
Abstract Independently, both 5-aminolevulinic acid (5-ALA) and intraoperative
neuromonitoring (IONM) have been shown to improve outcomes with high-grade gliomas …

[HTML][HTML] Enhancing Glioblastoma Resection with NIR Fluorescence Imaging: A Systematic Review

HM Mansour, S Shah, TM Aguilar, M Abdul-Muqsith… - Cancers, 2024 - mdpi.com
Glioblastoma (GB) is among the most aggressive and difficult-to-treat brain tumors, with a
median survival of only 12–15 months despite maximal treatments, including surgery …

Towards an established intraoperative oncological favorable tool: results of fluorescein-guided resection from a monocentric, prospective series of 93 primary …

J Falco, E Rubiu, M Broggi, M Farinotti… - Journal of Clinical …, 2022 - mdpi.com
It is commonly reported that maximizing surgical resection of contrast-enhancing regions in
patients with glioblastoma improves overall survival. Efforts to achieve an improved rate of …

[HTML][HTML] Preoperative map** techniques for brain tumor surgery: a systematic review

A Leone, F Carbone, U Spetzger… - Frontiers in …, 2025 - pmc.ncbi.nlm.nih.gov
Accurate preoperative map** is crucial for maximizing tumor removal while minimizing
damage to critical brain functions during brain tumor surgery. Navigated transcranial …

Advances in intraoperative glioma tissue sampling and infiltration assessment

NN Al-Adli, JS Young, K Scotford, YE Sibih, J Payne… - Brain Sciences, 2023 - mdpi.com
Gliomas are infiltrative brain tumors that often involve functional tissue. While maximal safe
resection is critical for maximizing survival, this is challenged by the difficult intraoperative …