Tumor cell infiltration into the brain in glioblastoma: from mechanisms to clinical perspectives
Simple Summary The estimated survival time for glioblastoma patients is extremely low; only
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
Surgical management of Glioma Grade 4: technical update from the neuro-oncology section of the Italian Society of Neurosurgery (SINch®): a systematic review
Purpose The extent of resection (EOR) is an independent prognostic factor for overall
survival (OS) in adult patients with Glioma Grade 4 (GG4). The aim of the neuro-oncology …
survival (OS) in adult patients with Glioma Grade 4 (GG4). The aim of the neuro-oncology …
Fluorescence-guided surgery in glioblastoma: 5-ALA, SF or both? Differences between fluorescent dyes in 99 consecutive cases
P Zeppa, R De Marco, M Monticelli, A Massara… - Brain Sciences, 2022 - mdpi.com
Background: Glioblastoma (GBM) is the most common primary brain tumor. The extent of
resection (EOR) has been claimed as one of the most important prognostic factors …
resection (EOR) has been claimed as one of the most important prognostic factors …
A systematic review of amino acid PET imaging in adult-type high-grade glioma surgery: a neurosurgeon's perspective
Simple Summary Several advantages of molecular imaging, namely, positron emission
tomography (PET), have been already described in different settings of glioma management …
tomography (PET), have been already described in different settings of glioma management …
[HTML][HTML] Single mesenchymal stromal cell migration tracking into glioblastoma using photoconvertible vesicles
Reliable cell labeling and tracking techniques are imperative for elucidating the intricate and
ambiguous interactions between mesenchymal stromal cells (MSCs) and tumors. Here, we …
ambiguous interactions between mesenchymal stromal cells (MSCs) and tumors. Here, we …
Resection of the contrast-enhancing tumor in diffuse gliomas bordering eloquent areas using electrophysiology and 5-ALA fluorescence: evaluation of resection rates …
DR Peters, F Halimi, K Ozduman, M Levivier… - Neurosurgical …, 2023 - Springer
Abstract Independently, both 5-aminolevulinic acid (5-ALA) and intraoperative
neuromonitoring (IONM) have been shown to improve outcomes with high-grade gliomas …
neuromonitoring (IONM) have been shown to improve outcomes with high-grade gliomas …
[HTML][HTML] Enhancing Glioblastoma Resection with NIR Fluorescence Imaging: A Systematic Review
HM Mansour, S Shah, TM Aguilar, M Abdul-Muqsith… - Cancers, 2024 - mdpi.com
Glioblastoma (GB) is among the most aggressive and difficult-to-treat brain tumors, with a
median survival of only 12–15 months despite maximal treatments, including surgery …
median survival of only 12–15 months despite maximal treatments, including surgery …
Towards an established intraoperative oncological favorable tool: results of fluorescein-guided resection from a monocentric, prospective series of 93 primary …
J Falco, E Rubiu, M Broggi, M Farinotti… - Journal of Clinical …, 2022 - mdpi.com
It is commonly reported that maximizing surgical resection of contrast-enhancing regions in
patients with glioblastoma improves overall survival. Efforts to achieve an improved rate of …
patients with glioblastoma improves overall survival. Efforts to achieve an improved rate of …
[HTML][HTML] Preoperative map** techniques for brain tumor surgery: a systematic review
A Leone, F Carbone, U Spetzger… - Frontiers in …, 2025 - pmc.ncbi.nlm.nih.gov
Accurate preoperative map** is crucial for maximizing tumor removal while minimizing
damage to critical brain functions during brain tumor surgery. Navigated transcranial …
damage to critical brain functions during brain tumor surgery. Navigated transcranial …
Advances in intraoperative glioma tissue sampling and infiltration assessment
NN Al-Adli, JS Young, K Scotford, YE Sibih, J Payne… - Brain Sciences, 2023 - mdpi.com
Gliomas are infiltrative brain tumors that often involve functional tissue. While maximal safe
resection is critical for maximizing survival, this is challenged by the difficult intraoperative …
resection is critical for maximizing survival, this is challenged by the difficult intraoperative …