Applications of genome‐scale metabolic reconstructions
The availability and utility of genome‐scale metabolic reconstructions have exploded since
the first genome‐scale reconstruction was published a decade ago. Reconstructions have …
the first genome‐scale reconstruction was published a decade ago. Reconstructions have …
Basic and applied uses of genome‐scale metabolic network reconstructions of Escherichia coli
The genome‐scale model (GEM) of metabolism in the bacterium Escherichia coli K‐12 has
been in development for over a decade and is now in wide use. GEM‐enabled studies of E …
been in development for over a decade and is now in wide use. GEM‐enabled studies of E …
Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence
B Steeb, B Claudi, NA Burton, P Tienz, A Schmidt… - PLoS …, 2013 - journals.plos.org
Pathogen access to host nutrients in infected tissues is fundamental for pathogen growth
and virulence, disease progression, and infection control. However, our understanding of …
and virulence, disease progression, and infection control. However, our understanding of …
Network synchronization landscape reveals compensatory structures, quantization, and the positive effect of negative interactions
T Nishikawa, AE Motter - Proceedings of the National …, 2010 - National Acad Sciences
Synchronization, in which individual dynamical units keep in pace with each other in a
decentralized fashion, depends both on the dynamical units and on the properties of the …
decentralized fashion, depends both on the dynamical units and on the properties of the …
The molecular origins of evolutionary innovations
A Wagner - Trends in Genetics, 2011 - cell.com
The history of life is a history of evolutionary innovations, qualitatively new phenotypic traits
that endow their bearers with new, often game-changing abilities. We know many individual …
that endow their bearers with new, often game-changing abilities. We know many individual …
The renaissance of continuous culture in the post-genomics age
AT Bull - Journal of Industrial Microbiology and Biotechnology, 2010 - academic.oup.com
The development of continuous culture techniques 60 years ago and the subsequent
formulation of theory and the diversification of experimental systems revolutionised …
formulation of theory and the diversification of experimental systems revolutionised …
Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052
Background Solventogenic clostridia offer a sustainable alternative to petroleum-based
production of butanol--an important chemical feedstock and potential fuel additive or …
production of butanol--an important chemical feedstock and potential fuel additive or …
Improving the iMM904 S. cerevisiae metabolic model using essentiality and synthetic lethality data
AR Zomorrodi, CD Maranas - BMC systems biology, 2010 - Springer
Background Saccharomyces cerevisiae is the first eukaryotic organism for which a multi-
compartment genome-scale metabolic model was constructed. Since then a sequence of …
compartment genome-scale metabolic model was constructed. Since then a sequence of …
Control and synchronization of neuron ensembles
Synchronization of oscillations is a phenomenon prevalent in natural, social, and
engineering systems. Controlling synchronization of oscillating systems is motivated by a …
engineering systems. Controlling synchronization of oscillating systems is motivated by a …
Load-induced modulation of signal transduction networks
Biological signal transduction networks are commonly viewed as circuits that pass along
information—in the process amplifying signals, enhancing sensitivity, or performing other …
information—in the process amplifying signals, enhancing sensitivity, or performing other …