The use of hydrogels has garnered significant interest as biomaterial and drug delivery
platforms for anti-infective applications. For decades antimicrobial peptides have been …

Introduction Proteus mirabilis is a key pathobiont in catheter-associated urinary tract
infections (CA-UTIs), which is well known to form crystalline biofilms that occlude catheters …

The adherence of Proteus mirabilis to the surface of urinary catheters leads to colonization
and eventual blockage of the catheter lumen by unique crystalline biofilms produced by …

The glucagon-like peptide 1 receptor (GLP-1R) is a member of the family (or class) B G-
protein-coupled receptor (GPCR). The receptor is a regulator of insulin and a key target in …

Medical devices such as venous catheters (VCs) and urinary catheters (UCs) are widely
used in the hospital setting. However, the implantation of these devices is often …

Designing and develo** small organic molecules for use as urease inhibitors is
challenging due to the need for ecosystem sustainability and the requirement to prevent …

Antimicrobial resistance is a public health threat with an increasing expression in low-and
middle-income countries such as Cape Verde. In this country, there is an overpopulation of …

Hyperammonemia is characterized by the accumulation of ammonia within the bloodstream
upon liver injury. Left untreated, hyperammonemia contributes to conditions such as hepatic …

Polyurethane (PU) ureteral stents are used in clinics to maintain the ureteral patency. Due to
biofilm formation and encrustation complications, long-term clinical usage has been limited …

Urease enzyme is an infectious factor that provokes the growth and colonization of virulence
pathogenic bacteria in humans. To overcome the deleterious effects of bacterial infections …