[HTML][HTML] Macrophage polarization and reprogramming in acute inflammation: a redox perspective

S Pérez, S Rius-Pérez - Antioxidants, 2022‏ - mdpi.com
Macrophage polarization refers to the process by which macrophages can produce two
distinct functional phenotypes: M1 or M2. The balance between both strongly affects the …

NLRP3 Inflammasome: a key contributor to the inflammation formation

WJ Zhang, KY Li, Y Lan, HY Zeng, SQ Chen… - Food and Chemical …, 2023‏ - Elsevier
Inflammation is an important part of the development of various organ diseases. The
inflammasome, as an innate immune receptor, plays an important role in the formation of …

Turmeric-derived nanovesicles as novel nanobiologics for targeted therapy of ulcerative colitis

C Gao, Y Zhou, Z Chen, H Li, Y **ao, W Hao… - …, 2022‏ - pmc.ncbi.nlm.nih.gov
Rationale: Ulcerative colitis (UC), a typical kind of inflammatory bowel disease (IBD), is an
idiopathic chronic intestinal inflammation. Conventional therapeutic strategies mainly focus …

Retinal Microenvironment‐Protected Rhein‐GFFYE Nanofibers Attenuate Retinal Ischemia‐Reperfusion Injury via Inhibiting Oxidative Stress and Regulating …

Z Zhang, S Peng, T Xu, J Liu, L Zhao, H Xu… - Advanced …, 2023‏ - Wiley Online Library
Retinal ischemia is involved in the occurrence and development of various eye diseases,
including glaucoma, diabetic retinopathy, and central retinal artery occlusion. To the best of …

Enhanced mechanical strength and sustained drug release in carrier‐free silver‐coordinated anthraquinone natural antibacterial anti‐inflammatory hydrogel for …

X Liang, L Ding, J Ma, J Li, L Cao, H Liu… - Advanced …, 2024‏ - Wiley Online Library
The persistent challenge of healing infectious wounds and the rise of bacterial resistance
represent significant hurdles in contemporary medicine. In this study, based on the natural …

A potential therapeutic approach for ulcerative colitis: targeted regulation of macrophage polarization through phytochemicals

K Wang, T Mao, X Lu, M Wang, Y Yun, Z Jia… - Frontiers in …, 2023‏ - frontiersin.org
Ulcerative colitis (UC), a type of inflammatory bowel disease characterized by recurring and
incurable symptoms, causes immense suffering and economic burden for patients due to the …

Irisin drives macrophage anti-inflammatory differentiation via JAK2-STAT6-dependent activation of PPARγ and Nrf2 signaling

Y Tu, J Liu, D Kong, X Guo, J Li, Z Long, J Peng… - Free Radical Biology …, 2023‏ - Elsevier
Irisin is an exercise-induced myokine that alleviates inflammation and obesity. The induction
of anti-inflammatory (M2) macrophage is facilitated for treatment of sepsis and associated …

[HTML][HTML] Chronic kidney disease and NLRP3 inflammasome: pathogenesis, development and targeted therapeutic strategies

G Huang, Y Zhang, Y Zhang, Y Ma - Biochemistry and biophysics reports, 2023‏ - Elsevier
Chronic kidney disease (CKD) is a global health concern and public health priority. The
condition often involves inflammation due to the accumulation of toxins and the reduced …

Red/NIR‐I‐Fluorescence Carbon Dots Based on Rhein with Active Oxygen Scavenging and Colitis Targeting for UC Therapeutics

J **a, J Wang, F Liu, Z Chen, C Chen… - Advanced …, 2024‏ - Wiley Online Library
Ulcerative colitis (UC) is a chronic inflammatory disease with uncontrolled inflammation and
demage to the intestinal barrier. Rhein, a bioactive compound in traditional Chinese …

Traditional Chinese medicine in regulating macrophage polarization in immune response of inflammatory diseases

S Chen, J Zeng, R Li, Y Zhang, Y Tao, Y Hou… - Journal of …, 2024‏ - Elsevier
Ethnopharmacological relevance Numerous studies have demonstrated that various
traditional Chinese medicines (TCMs) exhibit potent anti-inflammatory effects against …