Preclinical testing platforms for mechanical thrombectomy in stroke: a review on phantoms, in-vivo animal, and cadaveric models

Y Liu, M Abbasi, JLA Larco, R Kadirvel… - Journal of …, 2021 - jnis.bmj.com
Preclinical testing platforms have been instrumental in the research and development of
thrombectomy devices. However, there is no single model which fully captures the …

[HTML][HTML] Healthcare Application of Failure Mode and Effect Analysis (FMEA): Is There Room in the Infectious Disease Setting? A Sco** Review

M Vecchia, P Sacchi, LN Marvulli, L Ragazzoni… - Healthcare, 2025 - mdpi.com
Background: Failure mode and effect analysis (FMEA) is a valuable risk analysis tool aimed
at predicting the potential failures of a system and preventing them from occurring. Since its …

Arterial collapse during thrombectomy for stroke: clinical evidence and experimental findings in human brains and in vivo models

Y Liu, D Gebrezgiabhier, Y Zheng, AJ Shih… - American Journal of …, 2022 - ajnr.org
BACKGROUND AND PURPOSE: Aspiration thrombectomy has become a preferred
approach to recanalize large-vessel occlusion in stroke with a growing trend toward using …

Left ventricular systolic dysfunction predicts clinical prognosis in patients with acute ischemic stroke after intravenous thrombolysis

C Zhang, JC Wu, Z Tan, XL He, F Li, L Wang… - Aging (Albany …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Although intravenous recombinant tissue plasminogen activator (rt-PA)
thrombolysis is the most effective early treatment for acute ischemic stroke (AIS), outcomes …

Direct aspiration versus combined technique for distal medium-vessel occlusions: comparison on a human placenta model

J Burel, E Gerardin, C Papagiannaki, E Shotar… - American Journal of …, 2023 - ajnr.org
BACKGROUND AND PURPOSE: Mechanical thrombectomy appears to be a promising
option for distal medium-vessel occlusions, for which intravenous thrombolysis is effective …

Impact of stent-retriever tip design on distal embolization during mechanical thrombectomy: a randomized in vitro evaluation

J Li, R Tiberi, P Bhogal, JH Buhk, D Behme… - Journal of …, 2024 - jnis.bmj.com
Background Repeated number of passes, clot fragmentation, and distal embolization during
mechanical thrombectomy (MT) lead to worse clinical outcomes in acute ischemic stroke …

The effect of actuation frequency on clot integration with the Tigertriever device: A preliminary in vitro study

C Sadasivan, N Dashti, M Gopal… - Interventional …, 2024 - journals.sagepub.com
Background The Tigertriever stent retriever (Rapid Medical) can be actively expanded and
contracted by the operator, which allows for several actuation-related parameters to be …

Systemic immune inflammatory index is an independent predictor for the requirement of decompressive craniectomy in large artery occlusion acute ischemic stroke …

WC Li, YX Zhou, G Zhu, KL Zeng, HY Zeng… - Frontiers in …, 2022 - frontiersin.org
Background and purpose Following mechanical thrombectomy (MT), patients with large
artery occlusive acute ischemic stroke (LAO-AIS) often have cerebral herniation due to its …

Human “live cadaver” neurovascular model for proximal and distal mechanical thrombectomy in stroke

JLA Larco, SI Madhani, Y Liu, M Abbasi… - Journal of …, 2023 - jnis.bmj.com
Background Preclinical testing platforms that accurately replicate complex human cerebral
vasculature are critical to advance neurointerventional knowledge, tools, and techniques …

Current Approaches and Methods to Understand Acute Ischemic Stroke Treatment Using Aspiration Thrombectomy

P Patki, S Simon, F Costanzo, KB Manning - … Engineering and Technology, 2024 - Springer
Acute ischemic stroke occurs when a blood clot occludes a cerebral artery. Mechanical
interventions, primarily stent retrievers and aspiration thrombectomy, are used currently for …