Structured sparsity regularization for analyzing high-dimensional omics data

S Vinga - Briefings in Bioinformatics, 2021 - academic.oup.com
The development of new molecular and cell technologies is having a significant impact on
the quantity of data generated nowadays. The growth of omics databases is creating a …

Detecting prognostic biomarkers of breast cancer by regularized Cox proportional hazards models

L Li, ZP Liu - Journal of translational medicine, 2021 - Springer
Background The successful identification of breast cancer (BRCA) prognostic biomarkers is
essential for the strategic interference of BRCA patients. Recently, various methods have …

A novel method for financial distress prediction based on sparse neural networks with regularization

Y Chen, J Guo, J Huang, B Lin - International Journal of Machine Learning …, 2022 - Springer
Corporate financial distress is related to the interests of the enterprise and stakeholders.
Therefore, its accurate prediction is of great significance to avoid huge losses from them …

Cancer survival analysis using semi-supervised learning method based on Cox and AFT models with L1/2 regularization

Y Liang, H Chai, XY Liu, ZB Xu, H Zhang… - BMC medical …, 2016 - Springer
Background One of the most important objectives of the clinical cancer research is to
diagnose cancer more accurately based on the patients' gene expression profiles. Both Cox …

[HTML][HTML] Co-expression network analysis identified gene signatures in osteosarcoma as a predictive tool for lung metastasis and survival

H Zhang, L Guo, Z Zhang, Y Sun, H Kang… - Journal of …, 2019 - ncbi.nlm.nih.gov
Osteosarcoma (OS) is the most common primary bone tumor, whose poor prognosis is
mainly due to lung metastasis. The aim of this study is to build a practical and valid …

Hybrid L1/2+ 2 method for gene selection in the Cox proportional hazards model

HH Huang, Y Liang - Computer methods and programs in biomedicine, 2018 - Elsevier
Background and objective An important issue in genomic research is to identify the
significant genes that related to survival from tens of thousands of genes. Although Cox …

A preference-based multiobjective evolutionary approach for sparse optimization

H Li, Q Zhang, J Deng, ZB Xu - IEEE transactions on neural …, 2017 - ieeexplore.ieee.org
Iterative thresholding is a dominating strategy for sparse optimization problems. The main
goal of iterative thresholding methods is to find a so-called k-sparse solution. However, the …

Recurrence risk stratification and treatment strategies of patients with stage IVa‐b hypopharyngeal squamous cell carcinoma

Y Heng, C Xu, H Lin, X Zhu, L Zhou, M Zhang… - Head & …, 2022 - Wiley Online Library
Background Optimal treatment strategies for patients with stage IVa‐b hypopharyngeal
squamous cell carcinoma (HSCC) remain controversial. This study aimed to examine the …

Sparse Logistic Regression With L1/2 Penalty for Emotion Recognition in Electroencephalography Classification

DW Chen, R Miao, ZY Deng, YY Lu, Y Liang… - Frontiers in …, 2020 - frontiersin.org
Emotion recognition based on electroencephalography (EEG) signals is a current focus in
brain-computer interface research. However, the classification of EEG is difficult owing to …

Ensembling variable selectors by stability selection for the Cox model

QY Yin, JL Li, CX Zhang - Computational intelligence and …, 2017 - Wiley Online Library
As a pivotal tool to build interpretive models, variable selection plays an increasingly
important role in high‐dimensional data analysis. In recent years, variable selection …