The ever-increasing amount of biomedical data is enabling new large-scale studies, even
though ad hoc computational solutions are required. The most recent Machine Learning …

Implantable cardiovascular devices must undergo evaluation prior to animal testing and
clinical trials to ensure their performance and efficiency. Mock circulation loops (MCLs) are …

Goal: This work presents the development of a Hybrid Mock Circulatory Loop (HMCL) to
simulate hemodynamics at patient-specific level in terms of both 3D geometry and …

We aim to clarify our understanding of the process of state-space model input parameter
identification, known, within the clinical context, as model personalisation. To do so, we …

Detailed models of dynamical systems used in the life sciences may include hundreds of
state variables and many input parameters, often with physical meanings. Therefore …

Background and objective Parameters of mathematical models of the cardiovascular system
can be used to monitor cardiovascular state, such as total stressed blood volume status …

The physiological response to physical exercise is now recognized as an important tool
which can aid the diagnosis and treatment of cardiovascular diseases. This is due to the fact …

Purpose The main objective is to accelerate the mathematical modeling of complex systems
and offer the researchers an accessible and standardized platform for model sharing and …

Background Modelling and simulation may become clinically applicable tools for detailed
evaluation of the cardiovascular system and clinical decision-making to guide therapeutic …

End-systolic elastance of the left ventricle along with the waveforms of pressure and
volumetric blood flow in particular sectors of the circulatory system are of importance in …