The underlying study was carried out aiming at transdermal drug delivery (TDD) of
Goniothalamus macrophyllus as sono-photo-sensitizer (SPS) using microneedle (MN) …

This study evaluates the antitumor efficacy of hesperidin (Hesp) versus cisplatin (Cis) in
Ehrlich ascites carcinoma (EAC)-bearing mice, as well as its protective effect against Cis …

A series of new coumarin-N-heterocyclic hybrids, coumarin-quinolines 7a–e, coumarin-
acridines 10b, c and coumarin-neocryptolepines 13b, c were synthesized and evaluated for …

The study in vivo assessed the effect of pinostrobin on the histology, immunohistochemistry,
and biochemical parameters of thioacetamide (TAA) induced liver cirrhosis in Sprague …

Abstract Background Type 2 diabetes (T2DM) is a chronic metabolic disorder. Although
therapeutic pharmaceutical agents continue to advance, herbal medicines are potential …

This study evaluated the ameliorative potential of grape seed extract (GSE) against Ehrlich
solid tumor (EST)–induced hepatic tissue alterations in mice. The control group was infused …

Background and objective: Doxorubicin is a widely used chemotherapeutic agent that
causes oxidative stress leading to cardiotoxicity, hepatotoxicity, and nephrotoxicity. In …

Because the Ehrlich ascites carcinoma (EAC) model can accurately predict survival time and
is successful in creating neoplastic cells, it is frequently employed in experimental cancer …

Major depressive disorder and anxiety disorders are two mental diseases that are treated
with amitriptyline (AMT). AMT treatments induced liver, heart and testes toxicity; As a result …

Breast cancer remains the most common cause of cancer deaths among women globally.
Ehrlich solid tumor (EST) is a transplantable tumor model for simulating breast cancer. This …