The gut microbiome's role in the development, maintenance, and outcomes of sepsis
MW Adelman, MH Woodworth, C Langelier, LM Busch… - Critical care, 2020 - Springer
The gut microbiome regulates a number of homeostatic mechanisms in the healthy host
including immune function and gut barrier protection. Loss of normal gut microbial structure …
including immune function and gut barrier protection. Loss of normal gut microbial structure …
Pulmonary infections complicating ARDS
Pulmonary infection is one of the main complications occurring in patients suffering from
acute respiratory distress syndrome (ARDS). Besides traditional risk factors, dysregulation of …
acute respiratory distress syndrome (ARDS). Besides traditional risk factors, dysregulation of …
Dysbiosis of a microbiota–immune metasystem in critical illness is associated with nosocomial infections
Critically ill patients in intensive care units experience profound alterations of their gut
microbiota that have been linked to a high risk of hospital-acquired (nosocomial) infections …
microbiota that have been linked to a high risk of hospital-acquired (nosocomial) infections …
[HTML][HTML] Antibiotic resistance in the commensal human gut microbiota
Highlights•The human gut microbiota serves as a reservoir of antibiotic resistance
genes.•DNA sequencing and culture techniques are used to characterise the gut …
genes.•DNA sequencing and culture techniques are used to characterise the gut …
Extensive microbial diversity within the chicken gut microbiome revealed by metagenomics and culture
Background: The chicken is the most abundant food animal in the world. However, despite
its importance, the chicken gut microbiome remains largely undefined. Here, we exploit …
its importance, the chicken gut microbiome remains largely undefined. Here, we exploit …
The microbial ecology of Escherichia coli in the vertebrate gut
Escherichia coli has a rich history as biology's 'rock star', driving advances across many
fields. In the wild, E. coli resides innocuously in the gut of humans and animals but is also a …
fields. In the wild, E. coli resides innocuously in the gut of humans and animals but is also a …
Antimicrobial-associated harm in critical care: a narrative review
N Arulkumaran, M Routledge, S Schlebusch… - Intensive care …, 2020 - Springer
The belief that, for the individual patient, the benefit of prompt and continued use of
antimicrobials outweighs any potential harm is a significant barrier to improved stewardship …
antimicrobials outweighs any potential harm is a significant barrier to improved stewardship …
Metagenome-assembled genome binning methods with short reads disproportionately fail for plasmids and genomic islands
Metagenomic methods enable the simultaneous characterization of microbial communities
without time-consuming and bias-inducing culturing. Metagenome-assembled genome …
without time-consuming and bias-inducing culturing. Metagenome-assembled genome …
[HTML][HTML] Vancomycin-resistant Enterococcus faecium and the emergence of new sequence types associated with hospital infection
RF O'Toole, KWC Leong, V Cumming… - Research in …, 2023 - Elsevier
Enterococcus faecium is a major species in infections by vancomycin-resistant enterococci
(VRE). New variants of the pathogen have emerged and become dominant in healthcare …
(VRE). New variants of the pathogen have emerged and become dominant in healthcare …
The multifaceted lifestyle of enterococci: genetic diversity, ecology and risks for public health
V Cattoir - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Enterococci have become major human MDR nosocomial pathogens.•They are
found ubiquitously in non-human habitats (animals and the environment).•The main threat …
found ubiquitously in non-human habitats (animals and the environment).•The main threat …