Regeneration of dermis: scarring and cells involved

AL Rippa, EP Kalabusheva, EA Vorotelyak - Cells, 2019 - mdpi.com
There are many studies on certain skin cell specifications and their contribution to wound
healing. In this review, we provide an overview of dermal cell heterogeneity and their …

Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications

LA Milton, MS Viglione, LJY Ong, GP Nordin, YC Toh - Lab on a Chip, 2023 - pubs.rsc.org
Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled
architectures that repeatedly achieve biomimicry of biological phenomena. They are well …

Reprogramming of three-dimensional microenvironments for in vitro hair follicle induction

T Kageyama, A Shimizu, R Anakama, R Nakajima… - Science …, 2022 - science.org
During embryonic development, reciprocal interactions between epidermal and
mesenchymal layers trigger hair follicle morphogenesis. This study revealed that …

Reprograming the immune niche for skin tissue regeneration–from cellular mechanisms to biomaterials applications

R Mu, SC de Souza, Z Liao, L Dong, C Wang - Advanced Drug Delivery …, 2022 - Elsevier
Despite the rapid development of therapeutic approaches for skin repair, chronic wounds
such as diabetic foot ulcers remain an unaddressed problem that affects millions of people …

[HTML][HTML] Preparation of hair beads and hair follicle germs for regenerative medicine

T Kageyama, L Yan, A Shimizu, S Maruo, J Fukuda - Biomaterials, 2019 - Elsevier
Hair regenerative medicine is a promising approach for hair loss, during which autologous
follicular stem cells are transplanted into regions of hair loss to regenerate hairs. Because …

In vitro hair follicle growth model for drug testing

T Kageyama, H Miyata, J Seo, A Nanmo, J Fukuda - Scientific Reports, 2023 - nature.com
In vitro models of human hair follicle-like tissue could be fundamental tools to better
understand hair follicle morphogenesis and hair drug screening. During prenatal …

[HTML][HTML] Single-cell transcriptome profiling reveals dermal and epithelial cell fate decisions during embryonic hair follicle development

W Ge, SJ Tan, SH Wang, L Li, XF Sun, W Shen… - Theranostics, 2020 - ncbi.nlm.nih.gov
It is estimated that 50% of men and 25% of women worldwide suffer from hair loss, and
therefore it is of great significance to investigate the molecular pathways driving hair follicle …

Exosomes for hair growth and regeneration

Y Zhou, J Seo, S Tu, A Nanmo, T Kageyama… - Journal of bioscience …, 2024 - Elsevier
Exosomes are lipid bilayer vesicles, 30–200 nm in diameter, that are produced by cells and
play essential roles in cell–cell communication. Exosomes have been studied in several …

Hair grows hair: Dual-effective hair regrowth through a hair enhanced dissolvable microneedle patch cooperated with the pure yellow light irradiation

C Hong, G Zhang, W Zhang, J Liu, J Zhang… - Applied Materials …, 2021 - Elsevier
Inspired by the progress of seed germination (plowing, breeding and lighting), we presented
a similar collaborative hair growth technology, which integrated soluble microneedle …

Tissue engineering strategies for human hair follicle regeneration: How far from a hairy goal?

AR Castro, E Logarinho - Stem Cells Translational Medicine, 2020 - academic.oup.com
The demand for an efficient therapy for alopecia disease has fueled the hair research field in
recent decades. However, despite significant improvements in the knowledge of key …