RNA has sparked a revolution in modern medicine, with the potential to transform the way
we treat diseases. Recent regulatory approvals, hundreds of new clinical trials, the …

RNA medicines represent a paradigm shift in treatment and prevention of critical diseases of
global significance, eg, infectious diseases. The highly successful messenger RNA (mRNA) …

Vaccines play a critical role in the prevention of life-threatening infectious disease. However,
the development of effective vaccines against many immune-evading pathogens such as …

Background. In December 2019, the emergence of severe acute respiratory syndrome
coronavirus‐2 (SARS‐CoV‐2) led to the COVID‐19 pandemic, with millions of deaths …

Abstract Background Group A Streptococcus (Strep A) causes both uncomplicated and
severe invasive infections, as well as the post-infection complications acute rheumatic fever …

Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),
the viral spike protein (S) has become a target to describe appropriate epitopes for vaccine …

The highly pathogenic coronaviruses SARS-CoV-2 and SARS-CoV have led to the COVID-
19 pandemic and SARS outbreak, respectively. The receptor-binding domain (RBD) of the …

Background mRNA-1283 is an investigational coronavirus disease 2019 (COVID-19) mRNA
vaccine encoding the receptor-binding and N-terminal domains of the severe acute …

In a world grappling with the evolving variants of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), another emerging respiratory virus, respiratory syncytial virus …

The introduction of messenger ribonucleic acid (mRNA) vaccine technology represents a
significant breakthrough in immunology and public health, offering a novel approach to …