The development of COVID-19 treatment

Y Yuan, B Jiao, L Qu, D Yang, R Liu - Frontiers in immunology, 2023 - frontiersin.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused
a pandemic named coronavirus disease 2019 (COVID-19) that has become the greatest …

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X **e, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

COVID-19 and multisystem inflammatory syndrome in children and adolescents

L Jiang, K Tang, M Levin, O Irfan, SK Morris… - The Lancet Infectious …, 2020 - thelancet.com
As severe acute respiratory syndrome coronavirus 2 continues to spread worldwide, there
have been increasing reports from Europe, North America, Asia, and Latin America …

[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The sudden emergence of severe respiratory disease, caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …

Cytokine storm

DC Fajgenbaum, CH June - New England Journal of Medicine, 2020 - Mass Medical Soc
Cytokine Storm Cytokine storm, a life-threatening disorder involving cytokine elevations and
immune-cell hyperactivation, has various causes and is characterized by constitutional …

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …

Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as …

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

BJ Barnes, JM Adrover, A Baxter-Stoltzfus… - Journal of Experimental …, 2020 - rupress.org
Coronavirus disease 2019 (COVID-19) is a novel, viral-induced respiratory disease that in∼
10–15% of patients progresses to acute respiratory distress syndrome (ARDS) triggered by …

C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis

I Huang, R Pranata, MA Lim… - Therapeutic …, 2020 - journals.sagepub.com
Background: Patients critically ill with coronavirus disease-2019 (COVID-19) feature
hyperinflammation, and the associated biomarkers may be beneficial for risk stratification …