Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis

C Sandroni, T Cronberg, M Sekhon - Intensive care medicine, 2021 - Springer
Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent
reperfusion of the brain following resuscitation. In those who are admitted to intensive care …

[HTML][HTML] Clinical targeting of the cerebral oxygen cascade to improve brain oxygenation in patients with hypoxic–ischaemic brain injury after cardiac arrest

RL Hoiland, C Robba, DK Menon, G Citerio… - Intensive Care …, 2023 - Springer
The cerebral oxygen cascade includes three key stages:(a) convective oxygen delivery
representing the bulk flow of oxygen to the cerebral vascular bed;(b) diffusion of oxygen from …

Intimate partner violence-related brain injury: Unmasking and addressing the gaps

C Esopenko, D Jain, SP Adhikari… - Journal of …, 2024 - liebertpub.com
Intimate partner violence (IPV) is a significant, global public health concern. Women,
individuals with historically underrepresented identities, and disabilities are at high risk for …

A survey of neuromonitoring practices in North American pediatric intensive care units

MP Kirschen, K LaRovere, B Balakrishnan, J Erklauer… - Pediatric …, 2022 - Elsevier
Background Neuromonitoring is the use of continuous measures of brain physiology to
detect clinically important events in real-time. Neuromonitoring devices can be invasive or …

Post-cardiac arrest syndrome

J Penketh, JP Nolan - Journal of Neurosurgical Anesthesiology, 2023 - journals.lww.com
Post-cardiac arrest syndrome (PCAS) is a multicomponent entity affecting many who survive
an initial period of resuscitation following cardiac arrest. This focussed review explores …

Brain protection after anoxic brain injury: Is lactate supplementation helpful?

F Annoni, L Peluso, E Gouvêa Bogossian, J Creteur… - Cells, 2021 - mdpi.com
While sudden loss of perfusion is responsible for ischemia, failure to supply the required
amount of oxygen to the tissues is defined as hypoxia. Among several pathological …

Goal-directed care using invasive neuromonitoring versus standard of care after cardiac arrest: a matched cohort study

NA Fergusson, RL Hoiland, S Thiara… - Critical Care …, 2021 - journals.lww.com
PURPOSE: Following return of spontaneous circulation after cardiac arrest, hypoxic
ischemic brain injury is the primary cause of mortality and disability. Goal-directed care …

Critical care management of patients after cardiac arrest: a scientific statement from the American heart Association and neurocritical care Society

KG Hirsch, BS Abella, E Amorim, MK Bader… - Neurocritical care, 2024 - Springer
The critical care management of patients after cardiac arrest is burdened by a lack of high-
quality clinical studies and the resultant lack of high-certainty evidence. This results in …

Cerebrovascular pressure reactivity and intracranial pressure are associated with neurologic outcome after hypoxic-ischemic brain injury

R Balu, S Rajagopalan, S Baghshomali, M Kirschen… - Resuscitation, 2021 - Elsevier
Aim We evaluated the association of physiological parameters measured by intracranial
multimodality neuromonitoring with neurologic outcome in a consecutive series of patients …

Hypertonic sodium lactate infusion reduces vasopressor requirements and biomarkers of brain and cardiac injury after experimental cardiac arrest

F Annoni, F Su, L Peluso, I Lisi, E Caruso, F Pischiutta… - Critical Care, 2023 - Springer
Introduction Prognosis after resuscitation from cardiac arrest (CA) remains poor, with high
morbidity and mortality as a result of extensive cardiac and brain injury and lack of effective …