Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis
C Sandroni, T Cronberg, M Sekhon - Intensive care medicine, 2021 - Springer
Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent
reperfusion of the brain following resuscitation. In those who are admitted to intensive care …
reperfusion of the brain following resuscitation. In those who are admitted to intensive care …
[HTML][HTML] Clinical targeting of the cerebral oxygen cascade to improve brain oxygenation in patients with hypoxic–ischaemic brain injury after cardiac arrest
The cerebral oxygen cascade includes three key stages:(a) convective oxygen delivery
representing the bulk flow of oxygen to the cerebral vascular bed;(b) diffusion of oxygen from …
representing the bulk flow of oxygen to the cerebral vascular bed;(b) diffusion of oxygen from …
Intimate partner violence-related brain injury: Unmasking and addressing the gaps
Intimate partner violence (IPV) is a significant, global public health concern. Women,
individuals with historically underrepresented identities, and disabilities are at high risk for …
individuals with historically underrepresented identities, and disabilities are at high risk for …
A survey of neuromonitoring practices in North American pediatric intensive care units
MP Kirschen, K LaRovere, B Balakrishnan, J Erklauer… - Pediatric …, 2022 - Elsevier
Background Neuromonitoring is the use of continuous measures of brain physiology to
detect clinically important events in real-time. Neuromonitoring devices can be invasive or …
detect clinically important events in real-time. Neuromonitoring devices can be invasive or …
Post-cardiac arrest syndrome
J Penketh, JP Nolan - Journal of Neurosurgical Anesthesiology, 2023 - journals.lww.com
Post-cardiac arrest syndrome (PCAS) is a multicomponent entity affecting many who survive
an initial period of resuscitation following cardiac arrest. This focussed review explores …
an initial period of resuscitation following cardiac arrest. This focussed review explores …
Brain protection after anoxic brain injury: Is lactate supplementation helpful?
While sudden loss of perfusion is responsible for ischemia, failure to supply the required
amount of oxygen to the tissues is defined as hypoxia. Among several pathological …
amount of oxygen to the tissues is defined as hypoxia. Among several pathological …
Goal-directed care using invasive neuromonitoring versus standard of care after cardiac arrest: a matched cohort study
NA Fergusson, RL Hoiland, S Thiara… - Critical Care …, 2021 - journals.lww.com
PURPOSE: Following return of spontaneous circulation after cardiac arrest, hypoxic
ischemic brain injury is the primary cause of mortality and disability. Goal-directed care …
ischemic brain injury is the primary cause of mortality and disability. Goal-directed care …
Critical care management of patients after cardiac arrest: a scientific statement from the American heart Association and neurocritical care Society
The critical care management of patients after cardiac arrest is burdened by a lack of high-
quality clinical studies and the resultant lack of high-certainty evidence. This results in …
quality clinical studies and the resultant lack of high-certainty evidence. This results in …
Cerebrovascular pressure reactivity and intracranial pressure are associated with neurologic outcome after hypoxic-ischemic brain injury
R Balu, S Rajagopalan, S Baghshomali, M Kirschen… - Resuscitation, 2021 - Elsevier
Aim We evaluated the association of physiological parameters measured by intracranial
multimodality neuromonitoring with neurologic outcome in a consecutive series of patients …
multimodality neuromonitoring with neurologic outcome in a consecutive series of patients …
Hypertonic sodium lactate infusion reduces vasopressor requirements and biomarkers of brain and cardiac injury after experimental cardiac arrest
Introduction Prognosis after resuscitation from cardiac arrest (CA) remains poor, with high
morbidity and mortality as a result of extensive cardiac and brain injury and lack of effective …
morbidity and mortality as a result of extensive cardiac and brain injury and lack of effective …