Reconstructing computational system dynamics from neural data with recurrent neural networks

D Durstewitz, G Koppe, MI Thurm - Nature Reviews Neuroscience, 2023 - nature.com
Computational models in neuroscience usually take the form of systems of differential
equations. The behaviour of such systems is the subject of dynamical systems theory …

Analysis methods for large-scale neuronal recordings

C Stringer, M Pachitariu - Science, 2024 - science.org
Simultaneous recordings from hundreds or thousands of neurons are becoming routine
because of innovations in instrumentation, molecular tools, and data processing software …

Attractor dynamics reflect decision confidence in macaque prefrontal cortex

S Wang, R Falcone, B Richmond, BB Averbeck - Nature Neuroscience, 2023 - nature.com
Decisions are made with different degrees of consistency, and this consistency can be
linked to the confidence that the best choice has been made. Theoretical work suggests that …

Causal evidence of a line attractor encoding an affective state

A Vinograd, A Nair, JH Kim, SW Linderman… - Nature, 2024 - nature.com
Continuous attractors are an emergent property of neural population dynamics that have
been hypothesized to encode continuous variables such as head direction and eye …

Encoding of female mating dynamics by a hypothalamic line attractor

M Liu, A Nair, N Coria, SW Linderman, DJ Anderson - Nature, 2024 - nature.com
Females exhibit complex, dynamic behaviours during mating with variable sexual receptivity
depending on hormonal status,,–. However, how their brains encode the dynamics of mating …

A line attractor encoding a persistent internal state requires neuropeptide signaling

G Mountoufaris, A Nair, B Yang, DW Kim, A Vinograd… - Cell, 2024 - cell.com
Internal states drive survival behaviors, but their neural implementation is poorly understood.
Recently, we identified a line attractor in the ventromedial hypothalamus (VMH) that …

Sleep and the hypothalamus

AR Adamantidis, L de Lecea - Science, 2023 - science.org
Neural substrates of wakefulness, rapid eye movement sleep (REMS), and non-REMS
(NREMS) in the mammalian hypothalamus overlap both anatomically and functionally with …

Sexually dimorphic dopaminergic circuits determine sex preference

A Wei, A Zhao, C Zheng, N Dong, X Cheng, X Duan… - Science, 2025 - science.org
Sociosexual preference is critical for reproduction and survival. However, neural
mechanisms encoding social decisions on sex preference remain unclear. In this study, we …

The multi-stage plasticity in the aggression circuit underlying the winner effect

R Yan, D Wei, A Varshneya, L Shan, B Dai, HJ Asencio… - Cell, 2024 - cell.com
Winning increases the readiness to attack and the probability of winning, a widespread
phenomenon known as the" winner effect." Here, we reveal a transition from target-specific …

Back to the continuous attractor

Á Ságodi, G Martín-Sánchez… - Advances in Neural …, 2025 - proceedings.neurips.cc
Continuous attractors offer a unique class of solutions for storing continuous-valued
variables in recurrent system states for indefinitely long time intervals. Unfortunately …