Azines, such as pyridines, quinolines, pyrimidines, and pyridazines, are widespread
components of pharmaceuticals. Their occurrence derives from a suite of physiochemical …

Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform
for molecular syntheses, enabling applications to natural product syntheses, late-stage …

The fields of C–H functionalization and photoredox catalysis have garnered enormous
interest and utility in the past several decades. Many different scientific disciplines have …

The site-selective C–H bond functionalization of heteroarenes can eventually provide
chemists with great techniques for editing and building complex molecular scaffolds. During …

The present review is devoted to summarizing the recent advances (2015–2017) in the field
of metal-catalysed group-directed C–H functionalisation. In order to clearly showcase the …

In the field of C–H bond functionalization chemistry, directed C–H bond activation strategies
are highly appreciated due to the high efficiency and selectivity of such reactions towards a …

Skeletal editing is a straightforward synthetic strategy for precise substitution or
rearrangement of atoms in core ring structures of complex molecules; it enables quick …

Carbon-hydrogen (C− H) functionalization of pyridines is a powerful tool for the rapid
construction and derivatization of many agrochemicals, pharmaceuticals, and materials …

Herein, we report a method for C3-selective C–H tri-and difluoromethylthiolation of
pyridines. The method relies on borane-catalyzed pyridine hydroboration for generation of …

Direct asymmetric functionalization of the pyridyl C–H bond represents a longstanding
challenge in organic chemistry. We herein describe the first enantioselective para-C–H …