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A perspective on brain-age estimation and its clinical promise
Brain-age estimation has gained increased attention in the neuroscientific community owing
to its potential use as a biomarker of brain health. The difference between estimated and …
to its potential use as a biomarker of brain health. The difference between estimated and …
A systematic review of multimodal brain age studies: Uncovering a divergence between model accuracy and utility
Brain aging is a complex, multifaceted process that can be challenging to model in ways that
are accurate and clinically useful. One of the most common approaches has been to apply …
are accurate and clinically useful. One of the most common approaches has been to apply …
Mind the gap: Performance metric evaluation in brain‐age prediction
Estimating age based on neuroimaging‐derived data has become a popular approach to
develo** markers for brain integrity and health. While a variety of machine‐learning …
develo** markers for brain integrity and health. While a variety of machine‐learning …
[HTML][HTML] Deep neural networks learn general and clinically relevant representations of the ageing brain
The discrepancy between chronological age and the apparent age of the brain based on
neuroimaging data—the brain age delta—has emerged as a reliable marker of brain health …
neuroimaging data—the brain age delta—has emerged as a reliable marker of brain health …
Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium
Schizophrenia (SZ) is associated with an increased risk of life-long cognitive impairments,
age-related chronic disease, and premature mortality. We investigated evidence for …
age-related chronic disease, and premature mortality. We investigated evidence for …
Individual variations in 'brain age'relate to early-life factors more than to longitudinal brain change
Brain age is a widely used index for quantifying individuals' brain health as deviation from a
normative brain aging trajectory. Higher-than-expected brain age is thought partially to …
normative brain aging trajectory. Higher-than-expected brain age is thought partially to …
Prediction of brain age using structural magnetic resonance imaging: A comparison of accuracy and test–retest reliability of publicly available software packages
Brain age prediction algorithms using structural magnetic resonance imaging (MRI) aim to
assess the biological age of the human brain. The difference between a person's …
assess the biological age of the human brain. The difference between a person's …
Deep relation learning for regression and its application to brain age estimation
Most deep learning models for temporal regression directly output the estimation based on
single input images, ignoring the relationships between different images. In this paper, we …
single input images, ignoring the relationships between different images. In this paper, we …
Benchmarking the generalizability of brain age models: challenges posed by scanner variance and prediction bias
Abstract Machine learning has been increasingly applied to neuroimaging data to predict
age, deriving a personalized biomarker with potential clinical applications. The scientific and …
age, deriving a personalized biomarker with potential clinical applications. The scientific and …
Explainable brain age prediction using covariance neural networks
In computational neuroscience, there has been an increased interest in develo** machine
learning algorithms that leverage brain imaging data to provide estimates of" brain age" for …
learning algorithms that leverage brain imaging data to provide estimates of" brain age" for …