Peptides with dual antimicrobial and anticancer activities
In recent years, the number of people suffering from cancer and multi-resistant infections has
increased, such that both diseases are already seen as current and future major causes of …
increased, such that both diseases are already seen as current and future major causes of …
Designing improved active peptides for therapeutic approaches against infectious diseases
Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …
few decades, pathogenic microorganisms' resistance to conventional drugs has been …
[HTML][HTML] Unraveling the bioactivity of anticancer peptides as deduced from machine learning
Cancer imposes a global health burden as it represents one of the leading causes of
morbidity and mortality while also giving rise to significant economic burden owing to the …
morbidity and mortality while also giving rise to significant economic burden owing to the …
[HTML][HTML] Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria
BP100 is a short cationic antimicrobial peptide with a mechanism of action dependent on
peptide–lipid interactions and microbial surface charge neutralization. Although active …
peptide–lipid interactions and microbial surface charge neutralization. Although active …
Antimicrobial peptides as potential therapeutics for breast cancer
Breast cancer is the most common and deadliest cancer in women worldwide. Although
notable advances have been achieved in the treatment of breast cancer, the overall survival …
notable advances have been achieved in the treatment of breast cancer, the overall survival …
How many antimicrobial peptide molecules kill a bacterium? The case of PMAP-23
Antimicrobial peptides (AMPs) kill bacteria mainly through the perturbation of their
membranes and are promising compounds to fight drug resistance. Models of the …
membranes and are promising compounds to fight drug resistance. Models of the …
Class IIa bacteriocins: diversity and new developments
Y Cui, C Zhang, Y Wang, J Shi, L Zhang, Z Ding… - International journal of …, 2012 - mdpi.com
Class IIa bacteriocins are heat-stable, unmodified peptides with a conserved amino acids
sequence YGNGV on their N-terminal domains, and have received much attention due to …
sequence YGNGV on their N-terminal domains, and have received much attention due to …
Predictive model of linear antimicrobial peptides active against gram-negative bacteria
Antimicrobial peptides (AMPs) have been identified as a potential new class of anti-
infectives for drug development. There are a lot of computational methods that try to predict …
infectives for drug development. There are a lot of computational methods that try to predict …
Simple squaramide receptors for highly efficient anion binding in aqueous media and transmembrane transport
G Picci, M Kubicki, A Garau, V Lippolis… - Chemical …, 2020 - pubs.rsc.org
A family of acyclic squaramide receptors (L1–L5) have been synthesised with the aim to
bind anions in a competitive solvent mixture and to evaluate how the presence of additional …
bind anions in a competitive solvent mixture and to evaluate how the presence of additional …
Enabling the discovery and virtual screening of potent and safe antimicrobial peptides. Simultaneous prediction of antibacterial activity and cytotoxicity
VV Kleandrova, JM Ruso… - ACS combinatorial …, 2016 - ACS Publications
Antimicrobial peptides (AMPs) represent promising alternatives to fight against bacterial
pathogens. However, cellular toxicity remains one of the main concerns in the early …
pathogens. However, cellular toxicity remains one of the main concerns in the early …