GRaSP: a graph-based residue neighborhood strategy to predict binding sites
Motivation The discovery of protein–ligand-binding sites is a major step for elucidating
protein function and for investigating new functional roles. Detecting protein–ligand-binding …
protein function and for investigating new functional roles. Detecting protein–ligand-binding …
ProSNEx: a web-based application for exploration and analysis of protein structures using network formalism
Abstract ProSNEx (Protein Structure Network Explorer) is a web service for construction and
analysis of Protein Structure Networks (PSNs) alongside amino acid flexibility, sequence …
analysis of Protein Structure Networks (PSNs) alongside amino acid flexibility, sequence …
The Role of Structural Bioinformatics in Understanding Tumor Necrosis Factor α-Interacting Protein Mechanisms in Chronic Inflammatory Diseases: A Review
Tumor necrosis factor α (TNF-α) is a multifunctional cytokine protein acknowledged as a vital
mediator in cell differentiation, proliferation, and survival. Additionally, TNF-α is a crucial …
mediator in cell differentiation, proliferation, and survival. Additionally, TNF-α is a crucial …
Proteus: An algorithm for proposing stabilizing mutation pairs based on interactions observed in known protein 3D structures
Background Protein engineering has many applications for industry, such as the
development of new drugs, vaccines, treatment therapies, food, and biofuel production. A …
development of new drugs, vaccines, treatment therapies, food, and biofuel production. A …
visGReMLIN: graph mining-based detection and visualization of conserved motifs at 3D protein-ligand interface at the atomic level
Background Interactions between proteins and non-proteic small molecule ligands play
important roles in the biological processes of living systems. Thus, the development of …
important roles in the biological processes of living systems. Thus, the development of …
ppiGReMLIN: a graph mining based detection of conserved structural arrangements in protein-protein interfaces
FC Queiroz, AMP Vargas, MGA Oliveira… - BMC …, 2020 - Springer
Abstract Background Protein-protein interactions (PPIs) are fundamental in many biological
processes and understanding these interactions is key for a myriad of applications including …
processes and understanding these interactions is key for a myriad of applications including …
Bioinformatics and Computational Biology Research at the Computer Science Department at UFMG
D Mariano, FC Carvalho, LL Bastos… - Journal of Information …, 2024 - sol.sbc.org.br
Bioinformatics is an emerging research field that encompasses the use of computational
methods, algorithms, and tools to solve life science problems. At the Laboratory of …
methods, algorithms, and tools to solve life science problems. At the Laboratory of …
ToxAnalyzer: a user-friendly web tool for interactive data analysis and visualization of chemical compounds from the comparative toxicogenomics database (CTD)™
Toxicology is a field of science that has undergone changes in recent years. Using modern
sequencing technologies, it went from an exclusive animal-based science to a field of data …
sequencing technologies, it went from an exclusive animal-based science to a field of data …