Regulatory mechanisms of microRNA expression

LF Gulyaeva, NE Kushlinskiy - Journal of translational medicine, 2016 - Springer
MicroRNAs (miRs, miRNAs) are small molecules of 18–22 nucleotides that serve as
important regulators of gene expression at the post-transcriptional level. One of the …

Evolutionarily conserved serum microRNAs predict radiation-induced fatality in nonhuman primates

W Fendler, B Malachowska, K Meghani… - Science translational …, 2017 - science.org
Effective planning for the medical response to a radiological or nuclear accident is complex.
Because of limited resources for medical countermeasures, the key would be to accurately …

Sex differences in radiation research

LP Taliaferro, RK Agarwal, CN Coleman, AL DiCarlo… - 2024 - Taylor & Francis
Abstract Purpose The Sex Differences in Radiation Research workshop addressed the role
of sex as a confounder in radiation research and its implication in real-world radiological …

Identification of miRNA signatures associated with radiation-induced late lung injury in mice

CJ Rogers, AI Lukaszewicz, J Yamada-Hanff… - PloS one, 2020 - journals.plos.org
Acute radiation exposure of the thorax can lead to late serious, and even life-threatening,
pulmonary and cardiac damage. Sporadic in nature, late complications tend to be difficult to …

Non-coding RNAs in hereditary kidney disorders

JX Zhou, X Li - International journal of molecular sciences, 2021 - mdpi.com
Single-gene defects have been revealed to be the etiologies of many kidney diseases with
the recent advances in molecular genetics. Autosomal dominant polycystic kidney disease …

[HTML][HTML] Downregulation of miR-199a-3p mediated by the CtBP2-HDAC1-FOXP3 transcriptional complex contributes to acute lung injury by targeting NLRP1

Z Chen, WH Dong, Q Chen, QG Li… - International Journal of …, 2019 - ncbi.nlm.nih.gov
Emerging evidence indicates that microRNAs (miRNAs) play fundamental roles in the
pathogenesis of multiple diseases, including acute lung injury (ALI). Here, we discovered …

Observation of unique circulating miRNA signatures in non-human primates exposed to total-body vs. whole thorax lung irradiation

CJ Rogers, EM Kyubwa, AI Lukaszewicz… - Radiation …, 2021 - meridian.allenpress.com
A radiological/nuclear (RAD-NUC) incident, especially in an urban setting, results in diverse
radiation-induced injuries due to heterogeneities in dose, the extent of partial-body …

[HTML][HTML] Inflammation-dependent downregulation of miR-532-3p mediates apoptotic signaling in human sarcopenia through targeting BAK1

FX Chen, Y Shen, Y Liu, HF Wang… - International Journal of …, 2020 - ncbi.nlm.nih.gov
Inflammation and apoptosis are considered as two major pathological causes of human
sarcopenia. The current understanding based on different models recognizes that apoptosis …

[HTML][HTML] Serum MicroRNAs as xerostomia biomarkers in patients with oropharyngeal cancer undergoing radiation therapy

B Tomasik, A Papis-Ubych, K Stawiski, J Fijuth… - International Journal of …, 2021 - Elsevier
Purpose Severe xerostomia is noted in the majority of patients irradiated for oropharyngeal
cancer. Extracellular microRNAs (miRNAs) may serve as effective tools allowing prediction …

Identification of miRNA associated with reduced survival after whole-thorax lung irradiation in non-human primates

CJ Rogers, EM Kyubwa, AI Lukaszewicz… - Radiation …, 2021 - meridian.allenpress.com
Thoracic exposure to ionizing radiation can lead to delayed injuries to the heart and lung
that are serious and even life-threatening. These injuries are difficult to predict since they …