In this review, the history of boron's early use in drugs, and the history of the use of boron
functional groups in medicinal chemistry applications are discussed. This includes …

A standard goal of medicinal chemists has been to discover efficient and potent drug
candidates with specific enzyme-inhibitor abilities. In this regard, boron-based bioactive …

Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …

The twentieth century ended with human African trypanosomiasis (HAT) epidemics raging
across many parts of Africa. Resistance to existing drugs was emerging, and many programs …

Background Human African trypanosomiasis (HAT) is an important public health problem in
sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need exists …

1. INTRODUCTION Benzoxaboroles, first obtained by Torssell in 1957, 1 remained
underestimated for a long time. The new beginning for these remarkable compounds took …

Structurally, boronic acids are trivalent boron-containing organic compounds that possess
one alkyl substituent (ie, a C–B bond) and two hydroxyl groups to fill the remaining valences …

Human trypanosomiasis and leishmaniasis are vector‐borne neglected tropical diseases
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …

Boron-containing compounds which possess unique and attractive properties have received
increasing attention from the pharmaceutical industry and academia recently. They have …

Abstract The World Health Organization 'Ending the neglect to attain the Sustainable
Development Goals: A road map for neglected tropical diseases 2021–2030'outlines the …