Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Psoriasis is one of the most common inflammatory skin diseases with a chronic, relapsing-
remitting course. The last decades of intense research uncovered a pathological network of …

Luteolin belongs to the group of flavonoids and can be found in flowers, herbs, vegetables
and spices. It plays an important role in defending plants, for example against UV radiation …

The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …

Interleukin (IL)-33 belongs to IL-1 cytokine family which is constitutively produced from the
structural and lining cells including fibroblasts, endothelial cells, and epithelial cells of skin …

Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Keratinocytes and skin immune cells are actively metabolizing nutrients present in their
microenvironment. This is particularly important in common chronic inflammatory skin …

Background Psoriasis is a common chronic inflammatory skin disorder that causes patches
of thick red skin and silvery scales and affects 1–3% of the population, which reduces …

The serine/threonine kinase mechanistic target of rapamycin (mTOR) plays a pivotal role in
the regulation of cell proliferation, survival, and motility in response to availability of energy …

PhosphoInositide-3 Kinase (PI3K) represents a family of different classes of kinases which
control multiple biological processes in mammalian cells, such as cell growth, proliferation …