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Fluorescence-guided surgery in the surgical treatment of gliomas: Past, present and future
R Sun, H Cuthbert, C Watts - Cancers, 2021 - mdpi.com
Simple Summary Gliomas are aggressive central nervous system tumours. The emergence
and recent widespread adoption of 5-aminolevulinic acid and fluorescence guided surgery …
and recent widespread adoption of 5-aminolevulinic acid and fluorescence guided surgery …
5-Aminolevulinic acid–shedding light on where to focus
NB Dadario, D Khatri, N Reichman, CD Nwagwu… - World Neurosurgery, 2021 - Elsevier
Background Surgical management of gliomas is predicated on “safe maximal resection”
across all histopathologic grades because progression-free survival and overall survival are …
across all histopathologic grades because progression-free survival and overall survival are …
Towards machine learning-based quantitative hyperspectral image guidance for brain tumor resection
Background Complete resection of malignant gliomas is hampered by the difficulty in
distinguishing tumor cells at the infiltration zone. Fluorescence guidance with 5-ALA assists …
distinguishing tumor cells at the infiltration zone. Fluorescence guidance with 5-ALA assists …
Polarimetric visualization of healthy brain fiber tracts under adverse conditions: ex vivo studies
O Rodríguez-Núñez, P Schucht, E Hewer… - Biomedical optics …, 2021 - opg.optica.org
We suggest using the wide-field imaging Mueller polarimetry to contrast optically anisotropic
fiber tracts of healthy brain white matter for the detection of brain tumor borders during …
fiber tracts of healthy brain white matter for the detection of brain tumor borders during …
Use of 5-ALA fluorescence–guided surgery versus white-light conventional microsurgery for the resection of newly diagnosed glioblastomas (RESECT study): a …
OBJECTIVE Only one phase III prospective randomized study, published in 2006, has
assessed the performance of 5-aminolevulinic acid (5-ALA) fluorescence–guided surgery …
assessed the performance of 5-aminolevulinic acid (5-ALA) fluorescence–guided surgery …
Characterization of autofluorescence and quantitative protoporphyrin IX biomarkers for optical spectroscopy-guided glioma surgery
D Black, S Kaneko, A Walke, S König, W Stummer… - Scientific Reports, 2021 - nature.com
Aminolevulinic acid (5-ALA)-mediated fluorescence does not effectively depict low grade
gliomas (LGG) or the infiltrative tumor portion of high-grade gliomas (HGG). While …
gliomas (LGG) or the infiltrative tumor portion of high-grade gliomas (HGG). While …
5-Aminolevulinic acid-induced porphyrin contents in various brain tumors: implications regarding imaging device design and their validation
BACKGROUND Fluorescence-guided resections using 5-aminolevulinic acid (5-ALA)-
induced tumor porphyrins have been established as an adjunct for malignant glioma surgery …
induced tumor porphyrins have been established as an adjunct for malignant glioma surgery …
A wearable fluorescence imaging device for intraoperative identification of human brain tumors
M Mohtasebi, C Huang, M Zhao… - IEEE Journal of …, 2023 - ieeexplore.ieee.org
Malignant glioma (MG) is the most common type of primary malignant brain tumors. Surgical
resection of MG remains the cornerstone of therapy and the extent of resection correlates …
resection of MG remains the cornerstone of therapy and the extent of resection correlates …
Machine learning-based prediction of glioma margin from 5-ALA induced PpIX fluorescence spectroscopy
Gliomas are infiltrative brain tumors with a margin difficult to identify. 5-ALA induced PpIX
fluorescence measurements are a clinical standard, but expert-based classification models …
fluorescence measurements are a clinical standard, but expert-based classification models …
Discrimination of infiltrative glioma boundary based on laser-induced breakdown spectroscopy
G Teng, Q Wang, H Zhang, W **angli, H Yang… - Spectrochimica acta part …, 2020 - Elsevier
Glioma is a kind of brain tumor which infiltrates from the primary tumor to surrounding
healthy tissue. Due to the difficulty in determining the tumor infiltrative boundary during …
healthy tissue. Due to the difficulty in determining the tumor infiltrative boundary during …