The prediction of cellular function from a genotype is a fundamental goal in biology. For
metabolism, constraint-based modelling methods systematize biochemical, genetic and …

The presence of spatial gradients in fundamental culture parameters, such as dissolved
gases, pH, concentration of substrates, and shear rate, among others, is an important …

Elementary mode analysis is a useful metabolic pathway analysis tool to identify the
structure of a metabolic network that links the cellular phenotype to the corresponding …

Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad
array of metabolic pathways employed for the production of primary and secondary …

In this study, a metabolic network describing the primary metabolism of Chlamydomonas
reinhardtii was constructed. By performing chemostat experiments at different growth rates …

Biomining with acidophilic microorganisms has been used at commercial scale for the
extraction of metals from various sulfide ores. With metal demand and energy prices on the …

Living cells can express different metabolic pathways that support growth. The criteria that
determine which pathways are selected in which environment remain unclear. One recurrent …

Elementary flux mode (EFM) analysis allows the unbiased decomposition of a metabolic
network into minimal functional units, making it a powerful tool for metabolic engineering …

Metabolic pathway analysis was carried out to predict the metabolic potential of
Corynebacterium glutamicum and Escherichia coli for the production of L-methionine. Based …

Background Three methods were developed for the application of stoichiometry-based
network analysis approaches including elementary mode analysis to the study of mass and …