[HTML][HTML] Molecular mimicry and autoimmunity

M Rojas, P Restrepo-Jiménez, DM Monsalve… - Journal of …, 2018 - Elsevier
Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents
may induce autoimmunity. It occurs when similarities between foreign and self-peptides …

Update on NAFLD genetics: from new variants to the clinic

E Trépo, L Valenti - Journal of hepatology, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of liver diseases in high-
income countries and the burden of NAFLD is increasing at an alarming rate. The risk of …

[PDF][PDF] Primary biliary cholangitis: 2018 practice guidance from the American Association for the Study of Liver Diseases

KD Lindor, CL Bowlus, J Boyer, C Levy, M Mayo - Hepatology, 2019 - Wiley Online Library
This American Association for the Study of Liver Diseases (AASLD) 2018 Practice Guidance
on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009 …

Primary biliary cholangitis

A Lleo, GQ Wang, ME Gershwin, GM Hirschfield - The Lancet, 2020 - thelancet.com
Primary biliary cholangitis is an autoimmune liver disease that predominantly affects women.
It is characterised by a chronic and destructive, small bile duct, granulomatous lymphocytic …

EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis

GM Hirschfield, U Beuers, C Corpechot, P Invernizzi… - Journal of …, 2017 - Elsevier
Primary biliary cholangitis (PBC) is a chronic inflammatory autoimmune cholestatic liver
disease, which when untreated will culminate in end-stage biliary cirrhosis. Diagnosis is …

Primary biliary cholangitis: pathogenesis and therapeutic opportunities

AF Gulamhusein, GM Hirschfield - Nature Reviews Gastroenterology & …, 2020 - nature.com
Primary biliary cholangitis is a chronic, seropositive and female-predominant inflammatory
and cholestatic liver disease, which has a variable rate of progression towards biliary …

A placebo-controlled trial of obeticholic acid in primary biliary cholangitis

F Nevens, P Andreone, G Mazzella… - … England Journal of …, 2016 - Mass Medical Soc
Background Primary biliary cholangitis (formerly called primary biliary cirrhosis) can
progress to cirrhosis and death despite ursodiol therapy. Alkaline phosphatase and bilirubin …

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

GM Hirschfield, JK Dyson, GJM Alexander… - Gut, 2018 - gut.bmj.com
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an
autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury …

Transancestral map** and genetic load in systemic lupus erythematosus

CD Langefeld, HC Ainsworth, DSC Graham… - Nature …, 2017 - nature.com
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and
ethnic disparities. We report a large transancestral association study of SLE using …

[HTML][HTML] Myalgic encephalomyelitis/chronic fatigue syndrome–evidence for an autoimmune disease

F Sotzny, J Blanco, E Capelli, J Castro-Marrero… - Autoimmunity …, 2018 - Elsevier
Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a frequent and
severe chronic disease drastically impairing life quality. The underlying pathomechanism is …