Burkitt lymphoma

C López, B Burkhardt, JKC Chan, L Leoncini… - Nature Reviews …, 2022 - nature.com
Burkitt lymphoma (BL) is an aggressive form of B cell lymphoma that can affect children and
adults. The study of BL led to the identification of the first recurrent chromosomal aberration …

EBV-associated diseases: Current therapeutics and emerging technologies

S Chakravorty, B Afzali, M Kazemian - Frontiers in Immunology, 2022 - frontiersin.org
EBV is a prevalent virus, infecting> 90% of the world's population. This is an oncogenic virus
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …

Stress-induced Epstein-Barr virus reactivation

DG Sausen, MS Bhutta, ES Gallo, H Dahari… - Biomolecules, 2021 - mdpi.com
Epstein-Barr virus (EBV) is typically found in a latent, asymptomatic state in
immunocompetent individuals. Perturbations of the host immune system can stimulate viral …

Epstein–Barr Virus (EBV) Epithelial Associated Malignancies: Exploring Pathologies and Current Treatments

O Shechter, DG Sausen, ES Gallo, H Dahari… - International Journal of …, 2022 - mdpi.com
Epstein–Barr virus (EBV) is one of eight known herpesviruses with the potential to infect
humans. Globally, it is estimated that between 90–95% of the population has been infected …

[HTML][HTML] Multi-dimensional characterization of immunological profiles in small cell lung cancer uncovers clinically relevant immune subtypes with distinct prognoses …

L Yang, Z Zhang, J Dong, Y Zhang, Z Yang… - Pharmacological …, 2023 - Elsevier
Small-cell lung cancer (SCLC) is generally considered a'homogenous' disease, with little
documented inter-tumor heterogeneity in treatment guidance or prognosis evaluation. The …

Immune-checkpoint inhibitors in B-cell lymphoma

M Armengol, JC Santos, M Fernández-Serrano… - Cancers, 2021 - mdpi.com
Simple Summary Immune-based treatment strategies, which include immune checkpoint
inhibition, have recently become a new frontier for the treatment of B-cell-derived lymphoma …

Immunosuppressive Tumor Microenvironment and Immunotherapy of Epstein–Barr Virus-Associated Malignancies

X Zheng, Y Huang, K Li, R Luo, M Cai, J Yun - Viruses, 2022 - mdpi.com
The Epstein–Barr virus (EBV) can cause different types of cancer in human beings when the
virus infects different cell types with various latent patterns. EBV shapes a distinct and …

Worldwide prevalence of Epstein–Barr virus in patients with Burkitt lymphoma: a systematic review and meta-analysis

MJ Al-Khreisat, NH Ismail, A Tabnjh, FA Hussain… - Diagnostics, 2023 - mdpi.com
Burkitt lymphoma (BL) is a form of B-cell malignancy that progresses aggressively and is
most often seen in children. While Epstein–Barr virus (EBV) is a double-stranded DNA virus …

Tumor-associated macrophages in lymphoma: From mechanisms to therapy

X **ong, X **e, Z Wang, Y Zhang, L Wang - International …, 2022 - Elsevier
Lymphoma is a common hematologic malignant tumor that originates from lymph nodes or
other lymphoid tissues. The tumor microenvironment (TME) plays an indispensable role in …

Epstein–Barr Virus—Associated Malignancies and Immune Escape: The Role of the Tumor Microenvironment and Tumor Cell Evasion Strategies

M Bauer, S Jasinski-Bergner, O Mandelboim… - Cancers, 2021 - mdpi.com
Simple Summary The Epstein–Barr virus, also termed human herpes virus 4, is a human
pathogenic double-stranded DNA virus. It is highly prevalent and has been linked to the …