The heterogeneity of tissue macrophages, in health and in disease, has become
increasingly transparent over the last decade. But with the plethora of data comes a natural …

Microglia are the primary innate immune cells in the CNS. In the healthy brain, they exhibit a
unique molecular homeostatic 'signature', consisting of a specific transcriptional profile and …

The proportion of advanced age patients undergoing surgical procedures is on the rise
owing to advancements in surgical and anesthesia technologies as well as an overall aging …

Microglia are the resident macrophage population of the central nervous system (CNS).
Adequate microglial function is crucial for a healthy CNS. Microglia are not only the first …

Microglial cells are the resident macrophages in the central nervous system. These cells of
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …

Microglia, the immune cells of the central nervous system, have long been a subject of study
in the Alzheimer's disease (AD) field due to their dramatic responses to the pathophysiology …

Microglial cells are the scions of foetal macrophages which invade the neural tube early
during embryogenesis. The nervous tissue environment instigates the phenotypic …

Microglial cells constitute the resident macrophage population of the CNS. Recent in vivo
studies have shown that microglia carry out active tissue scanning, which challenges the …

Microgliosis is a common response to multiple types of damage in the CNS. However, the
origin of the cells involved in this process is still controversial and the relative importance of …

Inflammation, a common denominator among the diverse list of neurodegenerative
diseases, has recently been implicated as a critical mechanism responsible for the …