RNA is often considered as being the vector for the transmission of genetic information from
DNA to the protein synthesis machinery. However, besides translation RNA participates in a …

With the characteristics of intrinsically free from photobleaching, blinking, and self-
quenching, Raman microscopy has become a powerful platform in detecting molecular …

The mRNA modification N6‐methyladenosine (m6A) is associated with multiple roles in cell
function and disease. The methyltransferases METTL3‐METTL14 and METTL16 act as …

Transcriptome analysis by RNA sequencing (RNA-seq) has become an indispensable
research tool in modern plant biology. Virtually all RNA-seq studies provide a snapshot of …

To understand the structure and ensuing function of RNA in various cellular processes,
researchers greatly rely on traditional as well as contemporary labeling technologies to …

We synthesized a small library of eighteen 5-substituted pyrimidine or 7-substituted 7-
deazapurine nucleoside triphosphates bearing methyl, ethynyl, phenyl, benzofuryl or …

The development of modular and efficient methods to functionalize RNA with biophysical
probes is very important in advancing the understanding of the structural and functional …

Recent developments in RNA labeling technology have provided viable tools to analyze
RNA synthesis, processing and function in cell-free and cellular environments. Notably …

Highlights•Enzyme-mediated tagging of RNA on the cotranscriptional and
posttranscriptional level.•Tolerant RNA polymerases accept modified nucleoside …

RNA plays critical roles in a wide range of physiological processes. For example, it is well
known that RNA plays an important role in regulating gene expression, cell proliferation, and …