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Heavy metal associated health hazards: An interplay of oxidative stress and signal transduction
Heavy metal-induced cellular and organismal toxicity have become a major health concern
in biomedical science. Indiscriminate use of heavy metals in different sectors, such as …
in biomedical science. Indiscriminate use of heavy metals in different sectors, such as …
[HTML][HTML] Disease-associated metabolic pathways affected by heavy metals and metalloid
Increased exposure to environmental heavy metals and metalloids and their associated
toxicities has become a major threat to human health. Hence, the association of these …
toxicities has become a major threat to human health. Hence, the association of these …
[HTML][HTML] Role of reactive oxygen species in cancer progression: molecular mechanisms and recent advancements
Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …
ROS production in normal cells is controlled by the appropriate regulation between the silver …
Reactive oxygen species and cancer paradox: To promote or to suppress?
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …
increasingly being appreciated as powerful signaling molecules involved in the regulation of …
Estimation of health risks associated with dietary cadmium exposure
S Satarug, DA Vesey, GC Gobe, KR Phelps - Archives of Toxicology, 2023 - Springer
In much of the world, currently employed upper limits of tolerable intake and acceptable
excretion of cadmium (Cd)(ECd/Ecr) are 0.83 µg/kg body weight/day and 5.24 µg/g …
excretion of cadmium (Cd)(ECd/Ecr) are 0.83 µg/kg body weight/day and 5.24 µg/g …
Reactive oxygen species (ROS) and cancer: Role of antioxidative nutraceuticals
Extensive research over the past half a century indicates that reactive oxygen species (ROS)
play an important role in cancer. Although low levels of ROS can be beneficial, excessive …
play an important role in cancer. Although low levels of ROS can be beneficial, excessive …
Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases
IT Lee, CM Yang - Biochemical pharmacology, 2012 - Elsevier
Reactive oxygen species (ROS) are products of normal cellular metabolism and are known
to act as second messengers. Under physiological conditions, ROS participate in …
to act as second messengers. Under physiological conditions, ROS participate in …
Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF
J Cheng, HL Yang, CJ Gu, YK Liu… - International …, 2019 - spandidos-publications.com
Angiogenesis is an essential process involved in various physiological, including
placentation, and pathological, including cancer and endometriosis, processes. Melatonin …
placentation, and pathological, including cancer and endometriosis, processes. Melatonin …
Oxidative stress and metal carcinogenesis
Occupational and environmental exposures to metals are closely associated with an
increased risk of various cancers. Although carcinogenesis caused by metals has been …
increased risk of various cancers. Although carcinogenesis caused by metals has been …
Oxygen-independent regulation of HIF-1: novel involvement of PI3K/AKT/mTOR pathway in cancer
F Agani, BH Jiang - Current cancer drug targets, 2013 - ingentaconnect.com
Studies on erythropoietin regulation led to discovery of hypoxia-inducible factor 1 (HIF-1), a
transcription factor which is central component of oxygen sensing mechanism in mammalian …
transcription factor which is central component of oxygen sensing mechanism in mammalian …