Natalizumab, a highly specific α4-integrin antagonist, is approved for treatment of patients
with active relapsing-remitting multiple sclerosis (RRMS). It is generally recommended for …

The human polyomaviruses, BK virus and JC virus, have long been associated with serious
diseases including polyomavirus nephropathy and progressive multifocal …

A lyophilised serum preparation with high anti-A and anti-B titres, 14/300, was evaluated for
its suitability to serve as a WHO Reference Reagent to standardise and control …

This report updates and combines earlier versions of guidelines for the prevention and
treatment of opportunistic infections (OIs) in HIV-infected adults (ie, persons aged> 18 years) …

Background: Mortality and morbidity related to AIDS have decreased among HIV-infected
patients taking highly active anti-retroviral therapy (HAART), but previous studies may have …

Background: Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection
that develops in immunosuppressed patients with HIV infection. Paradoxically, some of …

OBJECTIVE To determine the change of incidence and prevalence of neurological disorders
caused by the human immunodeficiency virus (HIV) and opportunistic infections in HIV …

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the brain
caused by the JC virus (JCV). PML usually occurs via reactivation of JCV when an immune …

Background: Accelerating the clearance of therapeutic monoclonal antibodies (mAbs) from
the body may be useful to address uncommon but serious complications from treatment …

Progressive multifocal leukoencephalopathy is caused by the JC polyomavirus (JCV) and is
one of the most feared complications of HIV-1 infection. Unlike other opportunistic infections …