Positron emission tomography: current challenges and opportunities for technological advances in clinical and preclinical imaging systems

JJ Vaquero, P Kinahan - Annual review of biomedical …, 2015‏ - annualreviews.org
Positron emission tomography (PET) imaging is based on detecting two time-coincident high-
energy photons from the emission of a positron-emitting radioisotope. The physics of the …

Latest advances in molecular imaging instrumentation

BJ Pichler, HF Wehrl… - Journal of Nuclear …, 2008‏ - jnm.snmjournals.org
This review concentrates on the latest advances in molecular imaging technology, including
PET, MRI, and optical imaging. In PET, significant improvements in tumor detection and …

NEMA NU 4-2008 comparison of preclinical PET imaging systems

AL Goertzen, Q Bao, M Bergeron… - Journal of nuclear …, 2012‏ - jnm.snmjournals.org
The National Electrical Manufacturers Association (NEMA) standard NU 4-2008 for
performance measurements of small-animal tomographs was recently published. Before this …

Performance evaluation of the MOLECUBES β-CUBE—a high spatial resolution and high sensitivity small animal PET scanner utilizing monolithic LYSO scintillation …

S Krishnamoorthy, E Blankemeyer… - Physics in Medicine …, 2018‏ - iopscience.iop.org
The MOLECUBES β-CUBE scanner is the newest amongst commercially available
preclinical PET scanners for dedicated small animal imaging. The scanner is compact …

Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery

J Terrovitis, R Lautamäki, M Bonios, J Fox… - Journal of the American …, 2009‏ - jacc.org
Objectives: The aim of this study was to quantify acute myocardial retention of cardiac-
derived stem cells (CDCs) and evaluate different delivery methods with positron emission …

Spatial resolution and sensitivity of the Inveon small-animal PET scanner

EP Visser, JA Disselhorst, M Brom… - Journal of Nuclear …, 2009‏ - jnm.snmjournals.org
The Inveon small-animal PET scanner is characterized by a large, 127-mm axial length and
a 161-mm crystal ring diameter. The associated high sensitivity is obtained by using all lines …

Simultaneous in vivo imaging with PET and SPECT tracers using a Compton-PET hybrid camera

M Uenomachi, M Takahashi, K Shimazoe… - Scientific Reports, 2021‏ - nature.com
Positron-emission tomography (PET) and single-photon-emission computed tomography
(SPECT) are well-established nuclear-medicine imaging methods used in modern medical …

Small animal PET: a review of what we have done and where we are going

RS Miyaoka, AL Lehnert - Physics in Medicine & Biology, 2020‏ - iopscience.iop.org
Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

Metabolic alterations in a rat model of takotsubo syndrome

N Godsman, M Kohlhaas, A Nickel… - Cardiovascular …, 2022‏ - academic.oup.com
Aims Cardiac energetic impairment is a major finding in takotsubo patients. We investigate
specific metabolic adaptations to direct future therapies. Methods and results An …

Small-animal PET: what is it, and why do we need it?

R Yao, R Lecomte, ES Crawford - Journal of nuclear medicine …, 2012‏ - tech.snmjournals.org
Small-animal PET refers to imaging of animals such as rats and mice using dedicated PET
scanners. Small-animal PET has been used extensively in modern biomedical research. It …