Osteoarthritis: pathogenic signaling pathways and therapeutic targets

Q Yao, X Wu, C Tao, W Gong, M Chen, M Qu… - Signal transduction and …, 2023 - nature.com
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Non-surgical management of knee osteoarthritis: comparison of ESCEO and OARSI 2019 guidelines

NK Arden, TA Perry, RR Bannuru, O Bruyère… - Nature Reviews …, 2021 - nature.com
Knee osteoarthritis (OA) is a heterogeneous disease associated with substantial effects on
quality of life, and its clinical management is difficult. Among the several available guidelines …

[HTML][HTML] CDC clinical practice guideline for prescribing opioids for pain—United States, 2022

D Dowell - MMWR. Recommendations and reports, 2022 - cdc.gov
This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …

2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee

SL Kolasinski, T Neogi, MC Hochberg… - Arthritis & …, 2020 - Wiley Online Library
Objective To develop an evidence‐based guideline for the comprehensive management of
osteoarthritis (OA) as a collaboration between the American College of Rheumatology …

[HTML][HTML] An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of …

O Bruyère, G Honvo, N Veronese, NK Arden… - Seminars in arthritis and …, 2019 - Elsevier
Abstract Objectives The European Society for Clinical and Economic Aspects of
Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) sought to revisit the …

Surgical and tissue engineering strategies for articular cartilage and meniscus repair

H Kwon, WE Brown, CA Lee, D Wang… - Nature Reviews …, 2019 - nature.com
Injuries to articular cartilage and menisci can lead to cartilage degeneration that ultimately
results in arthritis. Different forms of arthritis affect~ 50 million people in the USA alone, and it …

[PDF][PDF] Osteoarthritis is a serious disease

GA Hawker - Clin Exp Rheumatol, 2019 - clinexprheumatol.org
Osteoarthritis (OA) is the most common form of arthritis, affecting 1 in 3 people over age 65
and women more so than men. The prevalence of OA is rising due, in part, to the increasing …

What does best practice care for musculoskeletal pain look like? Eleven consistent recommendations from high-quality clinical practice guidelines: systematic review

I Lin, L Wiles, R Waller, R Goucke, Y Nagree… - British journal of sports …, 2020 - bjsm.bmj.com
Objectives To identify common recommendations for high-quality care for the most common
musculoskeletal (MSK) pain sites encountered by clinicians in emergency and primary care …

Paracetamol: a review of guideline recommendations

U Freo, C Ruocco, A Valerio, I Scagnol… - Journal of clinical …, 2021 - mdpi.com
Musculoskeletal pain conditions are age-related, leading contributors to chronic pain and
pain-related disability, which are expected to rise with the rapid global population aging …

Knee osteoarthritis: pathophysiology and current treatment modalities

JC Mora, R Przkora, Y Cruz-Almeida - Journal of pain research, 2018 - Taylor & Francis
For decades, multiple attempts to fully understand knee osteoarthritis pathophysiology and
natural history have been attempted. Despite the extensive amount of research regarding …