In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

After nearly four decades of research, a safe and effective HIV-1 vaccine remains elusive.
There are many reasons why the development of a potent and durable HIV-1 vaccine is …

Antiretroviral therapy can effectively block HIV-1 replication and prevent or reverse
immunodeficiency in HIV-1-infected individuals. However, viral replication resumes within …

HIV prevalence is increasing worldwide because people on antiretroviral therapy are living
longer, although new infections decreased from 3· 3 million in 2002, to 2· 3 million in 2012 …

Despite antiretroviral therapy (ART), human immunodeficiency virus (HIV)-1 persists in a
stable latent reservoir,, primarily in resting memory CD4+ T cells,. This reservoir presents a …

Understanding the mechanisms of HIV tissue persistence necessitates the ability to visualize
tissue microenvironments where infected cells reside; however, technological barriers limit …

Background The development of a safe and effective vaccine against the human
immunodeficiency virus type 1 (HIV-1) is critical to pandemic control. Methods In a …

This review examines the enormous progress that has been made in the past decade in
understanding the origin of HIV, HIV genetic variability, and the impact of global HIV diversity …

Acute HIV-1 Infection | New England Journal of Medicine Skip to main content Access provided
byTE WHATU ORA HEALTH NEW ZEALAND COUNTIES MANUKAU The New England …

Human immunodeficiency virus type 1 (HIV-1) infection persists despite years of
antiretroviral therapy (ART). To remove the stigma and burden of chronic infection …